UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 14A

Proxy Statement Pursuant to Section 14(a) of the Securities

Exchange Act of 1934 (Amendment No.     )

Filed by the Registrant    x                                  Filed by a Party other than the Registrant    ¨

Check the appropriate box:

 

¨

  Preliminary Proxy Statement  ¨  Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))

x

  Definitive Proxy Statement    

¨

  Definitive Additional Materials    

¨

  Soliciting Material Pursuant to §240.14a-12    

Corcept Therapeutics Incorporated

(Name of Registrant as Specified In Its Charter)

 

 

 

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

 

 

 

Payment of Filing Fee (Check the appropriate box):

 

xNo fee required.

 

¨Fee computed on table below per Exchange Act Rules 14a-6(i)(4) and 0-11.

 

 1)Title of each class of securities to which transaction applies:

 

 

 

 2)Aggregate number of securities to which transaction applies:

 

 

 

 3)Per unit price or other underlying value of transaction computed pursuant to Exchange Act Rule 0-11 (set forth the amount on which the filing fee is calculated and state how it was determined):

 

 

 

 4)Proposed maximum aggregate value of transaction:

 

 

 

 5)Total fee paid:

 

 

 

¨Fee paid previously with preliminary materials.

 

¨Check box if any part of the fee is offset as provided by Exchange Act Rule 0-11(a)(2) and identify the filing for which the offsetting fee was paid previously. Identify the previous filing by registration statement number, or the Form or Schedule and the date of its filing.

 

 1)Amount Previously Paid:

 

 

 

 2)Form, Schedule or Registration Statement No.:

 

 

 

 3)Filing Party:

 

 

 

 4)Date Filed:

 

 


Corcept Therapeutics Incorporated

149 Commonwealth Drive

Menlo Park, California 94025

 

 

Notice of Annual Meeting of Stockholders

To Be Held on June 23, 2010May 19, 2011

Dear Stockholder:

The Annual Meeting of Stockholders of Corcept Therapeutics, or the Company, will be held on Wednesday, June 23, 2010Thursday, May 19, 2011 at 10:8:00 a.m. local time at the Company’s headquarters located at 149 Commonwealth Drive, Menlo Park, CA 94025 for the following purposes, as more fully described in the accompanying Proxy Statement:

1. To elect seven directors to hold office until the 20112012 Annual Meeting of Stockholders and until their successors are qualified and elected.

2. To conduct a non-binding advisory vote on the compensation of our named executive officers as disclosed in this Proxy Statement (“say on pay”).

3. To conduct a non-binding advisory vote on the frequency of future say on pay advisory votes.

4. To ratify the appointment of Ernst & Young LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2010.2011.

3.5. To transact such other business as may properly come before the meeting or any adjournments or postponements thereof.

Only stockholders of record at the close of business on April 30, 201011, 2011 will be entitled to notice of, and to vote at, such meeting or any adjournments or postponements thereof.

 

By Order Of the Board of Directors,

/s/ Robert L. Roe, M.DM.D.

Robert L. Roe, M.D.

President and Secretary

Menlo Park, California

May 14, 2010April 15, 2011

Important Notice Regarding the Availability of Proxy Materials for the

Stockholder Meeting to be Held on June 23, 2010May 19, 2011

Our 20102011 Proxy Materials are available atwww.corcept.com/proxymaterials/2010.2011.

YOUR VOTE IS IMPORTANT!

WHETHER OR NOT YOU PLAN TO ATTEND THE MEETING, PLEASE VOTE YOUR SHARES BY INTERNET, BY TELEPHONE OR YOU CAN COMPLETE, SIGN, DATE AND MAIL PROMPTLY THE ACCOMPANYING PROXY CARD IN THE ENCLOSED RETURN ENVELOPE, WHICH REQUIRES NO POSTAGE IF MAILED IN THE UNITED STATES. THIS WILL ENSURE THE PRESENCE OF A QUORUM AT THE MEETING. IF YOU ATTEND THE MEETING, YOU MAY VOTE IN PERSON IF YOU WISH TO DO SO EVEN IF YOU HAVE PREVIOUSLY SENT IN YOUR PROXY CARD. PLEASE NOTE, HOWEVER, THAT IF YOUR SHARES ARE HELD OF RECORD BY A BROKER, BANK OR OTHER NOMINEE AND YOU WISH TO VOTE AT THE MEETING, YOU MUST OBTAIN FROM THE RECORD HOLDER A PROXY ISSUED IN YOUR NAME.


TABLE OF CONTENTS

PROXY STATEMENT

1

NOMINEES TO BOARD OF DIRECTORS

3

DIRECTOR NOT STANDING FOR RE-ELECTION

5

DIRECTOR NOMINATION

6

BOARD MEETINGS AND COMMITTEES

7

BOARD LEADERSHIP STRUCTURE AND ROLE IN RISK OVERSIGHT

8

COMMUNICATIONS WITH DIRECTORS

9

CODE OF ETHICS

9

COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

9

INFORMATION CONCERNING EXECUTIVE OFFICERS

9

SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

9

CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

12

SECTION 16(A) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

14

EXECUTIVE COMPENSATION

14

EQUITY COMPENSATION PLAN INFORMATION

27

DIRECTOR COMPENSATION

28

REPORT OF THE COMPENSATION COMMITTEE

30

REPORT OF THE AUDIT COMMITTEE

31

FEES OF THE INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

32

PROPOSALS TO BE ACTED UPON AT THE ANNUAL MEETING

32

OTHER MATTERS

35

STOCKHOLDER PROPOSALS FOR THE 2012 ANNUAL MEETING

35

AVAILABLE INFORMATION

36


Corcept Therapeutics Incorporated

149 Commonwealth Drive

Menlo Park, California 94025

650-327-3270

 

 

PROXY STATEMENT

 

 

20102011 ANNUAL MEETING OF STOCKHOLDERS

General

We are furnishing this Proxy Statement and the enclosed proxy in connection with the solicitation of proxies by our Board of Directors, or Board, for use at the Annual Meeting of Stockholders of Corcept Therapeutics Incorporated, or the Company, to be held on June 23, 2010May 19, 2011 at 10:8:00 a.m. local time, at our headquarters located at 149 Commonwealth Drive, Menlo Park, California 94025 and at any adjournments thereof, or the Annual Meeting. This proxy statement and accompanying proxy card are being first mailed to stockholders on or about May 21, 2010.April 18, 2011.

Who Can Vote

Only holders of our common stock as of the close of business on April 30, 2010,11, 2011, or the Record Date, are entitled to vote at the Annual Meeting. Stockholders who hold shares of our common stock in “street name” may vote at the Annual Meeting only if they hold a valid proxy from their broker.

Shares Outstanding and Quorum

As of the Record Date, there were 67,031,36283,968,540 shares of common stock outstanding. A majority of the outstanding shares of common stock entitled to vote at the Annual Meeting must be present in person or by proxy in order for there to be a quorum at the meeting. Stockholders of record who are present at the meeting in person or by proxy and who abstain from voting, including brokers holding customers’ shares of record who cause abstentions to be recorded at the meeting, will be included in the number of shares present at the meeting for purposes of determining whether a quorum is present.

Voting Rights

Each stockholder of record is entitled to one vote at the Annual Meeting for each share of common stock held by such stockholder on the Record Date. Stockholders do not have cumulative voting rights. Stockholders may vote their shares by using the proxy card enclosed with this Proxy Statement. All proxies we receive which are properly voted, whether by signed proxy card, by telephonic or internet voting, that have not been revoked will be voted in accordance with the instructions contained in the proxy. If a proxy is received which does not specify a vote or an abstention, the shares represented by that proxy will be voted (a) for the nominees to the Board listed on the proxy card and in this Proxy Statement, (b) for the approval, on a non-binding advisory basis, of the compensation of our named executive officers as disclosed in this Proxy Statement, (c) for the approval, on a non-binding advisory basis, of a triennial say on pay advisory vote and (d) for the ratification of the appointment of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2010.2011. We are not aware, as of the date hereof, of any matters to be voted upon at the Annual Meeting other than those stated in this Proxy Statement and the accompanying Notice of Annual Meeting of Stockholders. If any other matters are properly brought before the Annual Meeting, the enclosed proxy card gives discretionary authority to the persons named as proxies to vote the shares represented by the proxy card in their discretion.

Votes Required to Approve Each Proposal

Under Delaware law and our Amended and Restated Certificate of Incorporation and Amended and Restated Bylaws, if a quorum exists at the Annual Meeting, (a) the nominees for director who receive the greatest number

1


of votes cast will be elected to the Board and (b) the proposalproposals (1) to approve, on a non-binding advisory basis, the compensation of our named executive officers as disclosed in this proxy statement, (2) to approve, on a non-binding advisory basis, the frequency of future say on pay advisory votes and (3) to ratify the appointment of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 20102011 will be approved if iteach proposal receives the affirmative vote of the majority of the sharesvotes cast affirmatively or negatively. However, if none of common stock presentthe alternatives for the frequency of future say on pay advisory votes (one year, two years or represented and entitledthree years) receive a majority vote, we will consider the frequency that receives the greatest number of votes by stockholders to vote atbe the Annual Meeting. frequency that has been approved by stockholders.

Abstentions and broker non-votes will have no impact on the election of directors since they have not been cast in favor of or against any nominee. BrokerAbstentions and broker non-votes will likewise not have any effect on any of the proposalproposals to (a) approve, on a nonbinding advisory basis, the compensation of our named executive officers as disclosed in this Proxy Statement, (b) approve, on a nonbinding advisory basis, the frequency of future say on pay advisory votes or (c) ratify the appointment of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 20102011 because approval of the proposaleach of these proposals is based solely on the number of shares entitled to vote. Abstentions will have the same effect as votes cast against either of these proposals.affirmatively or negatively.

Revocability of Proxies

A stockholder of record may revoke a proxy at any time before it is voted at the Annual Meeting by (a) delivering a proxy revocation or another duly executed proxy bearing a later date to the Secretary of our Company at 149 Commonwealth Drive, Menlo Park, California 94025 or (b) attending the Annual Meeting and voting in person. Attendance at the Annual Meeting will not revoke a proxy unless the stockholder actually votes in person at the meeting.

Solicitation of Proxies

The proxy card accompanying this Proxy Statement is solicited by the Board. We will pay all of the costs of soliciting proxies. In addition to solicitation by mail, our officers, directors and employees may solicit proxies personally, or by telephone, without receiving additional compensation. We, if requested, will pay brokers, banks and other fiduciaries that hold shares of common stock for beneficial owners for their reasonable out-of-pocket expenses of forwarding these materials to stockholders.

Householding of Proxy Materials

Householding is a procedure approved by the Securities and Exchange Commission, or the SEC, under which stockholders who have the same address and last name and do not participate in electronic delivery of proxy materials will receive only one copy of our Proxy Statement from a company, single bank, broker or other intermediary, unless one or more of these stockholders notifies us, the bank, broker or other intermediary that they wish to continue to receive individual copies. At the present time, we do not “household” for any of our stockholders of record. However, as explained below, your bank, broker or other intermediary may be householding your account if you hold your shares in street name.

If you hold shares in street name, your bank, broker or other intermediary may be delivering only one copy of our Proxy Statement to multiple stockholders of the same household who share the same address, and may continue to do so, unless your bank, broker or other intermediary has received contrary instructions from one or more of the affected stockholders in the household. If you are such a beneficial holder, contact your bank, broker or other intermediary directly in order to receive a separate set of our proxy materials.

2


NOMINEES TO BOARD OF DIRECTORS

At the Annual Meeting, the stockholders will vote on the election of seven directors, each to serve for a one-year term until the annual meeting of stockholders in 20112012 and until their successors are qualified and elected.

The name, age as of April 30, 201010, 2011 and principal occupation of each person nominated for election to the Board, all of whom currently serve as our directors, are set forth below:

 

Name

  Age 

Occupation

James N. Wilson(3)

  6667  Chairman of the Board of ourthe Company

Joseph K. Belanoff, M.D.

  5253  Chief Executive Officer of ourthe Company

G. Leonard Baker, Jr.(2)

  6768  Venture Capitalist

Joseph C. Cook, Jr.(2) (3)

  6869  Executive/Investor

Patrick G. Enright(1)

  4849  Venture Capitalist

James A. HarperDavid L. Mahoney(1)(2)

  6256  Retired Pharmaceutical Executive

David L. Mahoney

55  Private Equity Investor

Joseph L. Turner(1)

59Independent Director

(1)Member of Audit Committee
(2)Member of Compensation Committee
(3)Member of Nominating and Corporate Governance Committee

The directors are elected at each annual meeting of stockholders, or special meeting in lieu thereof. The directors serve for a one-year term until the next annual meeting of stockholders and until their successors are elected and qualified. In addition to the information presented below regarding each director’s specific experience, qualifications, attributes and skills that led our Board to the conclusion that each individual should serve as a director, we also believe that all of our director nominees have a reputation for integrity, honesty and adherence to high ethical standards. They each have demonstrated business acumen and an ability to exercise sound judgment, as well as a commitment of service to us and our Board. Our Board believes that the backgrounds and qualifications of the directors, considered as a group, provides a significant composite mix of experience, knowledge and abilities that allows the Board to fulfill its responsibilities.

James N. Wilson has served as a director and as Chairman of theour Board since 1999. In addition, since 2005, Mr. Wilson has been the Chairman of the Board of NuGEN Technologies, Inc., a provider of systems for genomic analysis. From 2002 to 2009, he served as a director of Amylin Pharmaceuticals, Inc., a publicly-traded biopharmaceutical company, and from 1996 to 2001 Mr. Wilson was Chairman of the Board of Amira Medical, Inc., which was acquired by Hoffmann-La Roche A.G. From 1991 to 1994, he was Chief Operating Officer of Syntex Corporation, which was acquired by Roche Holding, Ltd. From 1989 to 1990, Mr. Wilson was Chairman and Chief Executive Officer of Neurex Corporation, which was acquired by Elan Corporation plc, and from 1982 to 1988, Mr. Wilson was Chief Executive Officer of LifeScan, Inc., which was acquired by Johnson & Johnson Company. Mr. Wilson received his B.A. and M.B.A. from the University of Arizona. Our Board selected Mr. Wilson to serve as a director because he brings to theour Board of Directors extensive experience in the biotechnology industry, evidenced by nearly 30 years of representing biotechnology companies as a director or officer.

Joseph K. Belanoff, M.D. is a co-founder of our company and has served as a member of theour Board and as our Chief Executive Officer since 1999. Dr. Belanoff is currently a clinical faculty member and has held various positions in the Department of Psychiatry and Behavioral Sciences at Stanford University since 1992. From 1997 to 2001, he served as the Director of Psychopharmacology at the outpatient division of the Palo Alto Veterans Affairs Hospital. Dr. Belanoff received his B.A. from Amherst College and his M.D. from Columbia University’s College of Physicians & Surgeons. AsOur Board selected Dr. Belanoff to serve as a director because, as our Chief Executive Officer, Dr. Belanoffhe brings expertise and knowledge regarding our business and operations to our Board of Directors. Dr. Belanoff also has expertise in clinical medicine and psychopharmacology.

G. Leonard Baker, Jr. has served as a member of theour Board of Directors since 1999. Since 1973, Mr. Baker has been a Managing Director of the General Partner of Sutter Hill Ventures, a venture capital firm. Mr. Baker currently serves on the boards of a number of private companies.companies, including Infomedics, Inc., Line 6, Inc., Roplast Industries, Yaolan, Ltd., Government Investment Corporation of Singapore Special Investments and the Government Investment Corporation of Singapore Pte Ltd, as well as Youku.com Inc., a publicly traded internet television company. Additionally, during the past five years Mr. Baker has served on the boards of publicly-traded companies Praecis Pharmaceuticals and Therma-Wave Inc., which was acquired in 2007 by KLA-Tencor Corp. Mr. Baker received his B.A. from Yale University and his M.B.A. from Stanford University. Our Board selected Mr. Baker to serve as a director because he has broad experience in advising companies, including expertise in capital raising, strategic transactions and operations.

Joseph C. Cook, Jr.has served as a member of theour Board of Directors since 2002. Mr. Cook is a founder and currently serves as Chairman of the Boarddirector of Ironwood Pharmaceuticals, Inc., or Ironwood, a publicly traded biotechnology company.company, and served as Chairman of its Board from 1998 to 2010. Mr. Cook is a principal, director and co-founder of Mountain Group Capital, LLC, a private investment company, and a principal, director and founder of The Limestone Fund, a recipient of the State of Tennessee TNInvestco award. He is a founder and serves as chairman of the board of Clinical Products, a private company marketing a medical food for people with diabetes. Mr. Cook served as chairman of Amylin Pharmaceuticals, Inc. from 1998 to 2009 and was chief executive officer from 1998 to 2003. He spent 28 years at Eli Lilly and Co., or Lilly, retiring from

3


Lilly in 1993 as a Group Vice-President. In 2009, Mr. Cook received the Pinnacle Award for Life Science Leadership from the Rady School of Management at the University of California at San Diego. In 1999, Mr. Cook also received from the University of Tennessee, The Nathan W. Dougherty Award for Distinguished Service in the Engineering Profession.Profession from the University of Tennessee. Mr. Cook received a Bachelor’s Degreehis B.S. in Engineering from the University of Tennessee in 1965. Our Board selected Mr. Cook to serve as a director because he brings to our Board of Directors extensive experience in the pharmaceutical industry.

Patrick G. Enright has served as a member of theour Board of Directors since April 2008. He is a founder of Longitude Capital Management Co., LLC, a venture capital firm focused on investments in biotechnology and has served as its Managing Director since 2006.2007. From 2002 through 2006, Mr. Enright was a Managing Director of Pequot Ventures where he co-led the life sciences investment practice. Prior to Pequot, he was a Managing Member responsible for the Delta Opportunity Fund, where he invested in privately-held and publicly-traded biotechnology companies, such as SUGEN, Inc. and Cephalon, Inc. Mr. Enright began his investment career at PaineWebber Development Corporation, a direct investment group focused primarily on biotechnology companies. Mr. Enright also has significant life sciences operations experience. He was CFOChief Financial Officer and Senior Vice President Business Development of Valentis, Inc. (now Urigen Pharmaceuticals, Inc.) and Senior Vice President Finance and Business Development of Boehringer Mannheim Pharmaceuticals (now F. Hoffmann-La Roche)Roche. Ltd.). Mr. Enright began his life sciences career 24 years ago at Sandoz (now Novartis)Novartis AG). He currently serves on the boardsBoards of Corcept and a number of privately-held companies.companies, including Infacare Pharmaceutical Corporation and Xanodyne Pharmaceuticals, Inc., as well as Jazz Pharmaceuticals, Inc., a publicly traded pharmaceutical company. Within the last five years, Mr. Enright has served within the last five years on the BoardBoards of Directors of Infacare Pharmaceuticals, Xanodyne Pharmaceuticals, Jazz Pharamceuticals,publicly-traded companies, including Threshold Pharmaceuticals, Inc., Sequenom, Inc., Valentis, Inc. (now Urigen Pharmaceuticals, Inc.), Codexis, Inc. and Valentis.MAP Pharmaceuticals, Inc. Mr. Enright holds anreceived his M.B.A. from the Wharton School of Business at the University of Pennsylvania and ahis B.S. in Biological Sciences from Stanford University. Our Board selected Mr. Enright to serve as a director because he has extensive knowledge of finance and experience in the biotechnology industry.

David L. Mahoney is a private equity investor who has served as a member of our Board since July 2004. From 1999 to 2001, Mr. Mahoney served as co-CEO of McKesson HBOC, Inc., a healthcare supply management and information technology company and as CEO of iMcKesson LLC, a healthcare management and connectivity company. He joined McKesson Corporation, or McKesson, in 1990 as Vice President for Strategic Planning. Prior to joining McKesson, Mr. Mahoney was a principal with McKinsey & Company, a management consulting firm, where he worked from 1981 to 1990. Mr. Mahoney serves on the Board of Symantec Corporation, a publicly-traded software technology company, including as a member of the Audit and

Compensation Committees. He also serves on the Board of Directors of several privately-held organizations including Adamas Pharmaceuticals, Inc., 20x200.com, San Francisco Museum of Modern Art and Mercy Corps. Mr. Mahoney served on the Board of Tercica, Inc., a pharmaceutical company (acquired by the Ipsen Group), from 2004 through 2008, including as a member of the Audit and Compensation committees. Mr. Mahoney also served on the Board of Directors of non-profit organizations Live Oak School, and NCPB, Inc., a public television and radio operator. Mr. Mahoney received his B.A. from Princeton University and his M.B.A. from Harvard University. Our Board selected Mr. Mahoney to serve as a director because he brings to our Board extensive experience in pharmaceutical distribution, fiscal management and in operating and advising technology companies.

Joseph L. Turner is a retired financial executive who has served as a member of our Board since August 2010. Mr. Turner was Senior Vice President of Finance and Administration and Chief Financial Officer at Myogen, Inc., a therapeutics company focused on cardiovascular disease, from 1999 until its acquisition by Gilead Sciences, Inc. in November 2006. Prior to Myogen, Inc., he served as Vice President, Finance and Chief Financial Officer at Centaur Pharmaceuticals, Inc., a privately-held biopharmaceutical company, from 1997 to 1999 and as Vice President, Finance and Chief Financial Officer of Cortech, Inc. from 1992 to 1997. From 1979 to 1991, Mr. Turner worked at Lilly, where he held a variety of financial management positions both within the United States and abroad. Mr. Turner is currently a member of the Board of Directors of Alexza Pharmaceuticals, Inc., or Alexza, and QLT, Inc., publicly traded biotechnology companies. Mr. Turner serves as the Chair of the Audit and Ethics Committee of Alexza and is a member of the Audit and Risk Committee of QLT, Inc. He also serves on the Board of Directors of Sequel Pharmaceuticals, Inc. and Kythera Biopharmaceuticals, Inc., privately held pharmaceutical companies. Mr. Turner also currently serves on the Board of Managers of Swarthmore College. Mr. Turner previously served on the Board of Directors and Audit Committee of SGX Pharmaceuticals, Inc., a publicly held biotechnology company that was acquired by Lilly, is a former director and Chairman of the Audit Committee of NovaCardia, Inc., a privately-held biotechnology company that was acquired by Merck & Co., Inc., and served on the Board of Directors of ApopLogic Pharmaceuticals, Inc., a privately held biotechnology company. Mr. Turner received his M.B.A. from the University of North Carolina at Chapel Hill, an M.A. in Molecular Biology from the University of Colorado at Boulder and a B.A. in Chemistry from Swarthmore College. Our Board selected Mr. Turner to serve as a director because he brings to our Board more than 30 years of experience in financial management and fiscal oversight of biotechnology companies.

There are no family relationships among any of our directors or executive officers.

DIRECTOR NOT STANDING FOR RE-ELECTION

The following current director has decided to retire from our Board as of the date of this Annual Meeting and is, therefore, not standing for re-election.

James A. Harper has served as a member of theour Board of Directorsand Compensation Committee since October 2004. Mr. Harper held various positions with Eli Lilly, from which he retired in 2004. Mr. Harper served as Group Vice President and Chief Marketing Officer from 2001 to 2004, and as President of the Diabetes and Growth Disorders Business Unit / Product Group from 1994 to 2001. He was a2001, as Vice President of Global Pharmaceutical Marketing from 1993 to 1994 and1994. Mr. Harper was President and CEO,Chief Executive Officer of Advanced Cardiovascular Systems, Inc. from 1991 to 1993. Mr. Harper also serves on the Board of Directors of Zymogenetics, Inc., including membership on the Audit and Compensation Committees, and the Board of Directors of Phenomix Corporation, a privately-held biotechnology company, where he serves as the Chairman of the Board and a member of the Compensation Committee. Zymogentetics, Inc. and Phenomix Corporation are both biotechnology companies. Mr. Harper served on the Board of Directors of Zymogenetics, Inc., a biotechnology company acquired by Bristol-Myers Squibb in 2010, including as a member of the Audit and Compensation Committees. He also served on the Board of Directors of Anesiva, Inc., a biotechnology company, from 2007 through 2008, including as a member of the Compensation Committee. He is also an advisor for Nomura Phase4 Ventures. Mr. Harper received his B.A. from Vanderbilt University and his M.B.A. from The Wharton School of Business. HeOur Board selected Mr. Harper to serve as a director because he has spentbrought to our Board over 30 years of experience in the pharmaceutical and healthcare industries and expertise in marketing.

David L. Mahoney is a private equity investor who has served as a member of the Board since July 2004. From 1999 to 2001, Mr. Mahoney served as co-CEO of McKesson HBOC, Inc., a healthcare supply management and information technology company and as CEO of iMcKesson LLC, a healthcare management and connectivity company. He joined McKesson Corporation in 1990 as Vice President for Strategic Planning. Prior to joining McKesson, Mr. Mahoney was a principal with McKinsey & Company where he worked from 1981 to 1990. He also serves on the Board of Directors of Symantec Corporation, Adamas Pharmaceuticals, San Francisco Museum of Modern Art, Mercy Corps and NCPB, Inc., a public television and radio operator. Mr. Mahoney served on the Board of Directors of Tercica, Inc., a pharmaceutical company, from 2004 through 2008, including as a member of the Audit and Compensation committees. Tercica was acquired by the Ipsen Group in 2008. Mr. Mahoney received his B.A. from Princeton University and his M.B.A. from Harvard University. Mr. Mahoney brings to our Board of Directors extensive experience in pharmaceutical distribution and in operating and advising technology companies.

There are no family relationships among any of our directors or executive officers.

4


DIRECTOR NOMINATION

The information below describes the criteria and process that the Nominating and Corporate Governance Committee uses to evaluate candidates to the Board.

Nominating and Corporate Governance Committee.    Our Nominating and Corporate Governance Committee currently consists of Joseph C. Cook, Jr. (Chairman) and James N. Wilson. The Nominating and Corporate Governance Committee did not meetmet once during 2009.2010. The Nominating and Corporate Governance Committee is responsible for identifying individuals qualified to serve as members of the Board, recommending to the independent members of the Board nominees for election as our directors and providing oversight with respect to corporate governance and ethical conduct. The Board has determined that Mr. Cook is an “independent director” for NASDAQ purposes. Although Mr. Wilson is our employee and therefore not an “independent director” for NASDAQ purposes, our director nomination process meets applicable NASDAQ requirements because our director nominees are selected by the independent members of the Board. The Nominating and Corporate Governance Committee has a written charter, a copy of which is available on our website at www.corcept.com.

The information below describes the criteria and process that the Nominating and Corporate Governance Committee uses to evaluate candidates to the Board.

Board Membership Criteria.    The Nominating and Corporate Governance Committee is responsible for assessing the appropriate balance of experience, skills and characteristics required of the Board. Nominees for director are selected on the basis of depth and breadth of experience, knowledge, integrity, ability to make independent analytical inquiries, understanding of our business environment, the willingness to devote adequate time to Board duties, the interplay of the candidate’s experience and skills with those of other Board members, and the extent to which the candidate would be a desirable addition to the Board and any Committees of the Board. Although there is no specific policy regarding diversity in identifying director nominees, both the Nominating and Corporate Governance Committee and the Board seek the talents and backgrounds that would be most helpful to us inwhen selecting director nominees. In particular, the Nominating and Corporate Governance Committee, when recommending director candidates to the full Board for nomination, may consider whether a director candidate, if elected, assists in achieving a mix of Board members that represents a diversity of background and experience. In addition, the Nominating and Corporate Governance Committee seeks to ensure that at least a majority of the directors are independent under the rules of the NasdaqNASDAQ Stock Market, that the Audit Committee and Compensation Committee are each composed entirely of independent directors, and that members of the Audit Committee possess such accounting and financial expertise as the NasdaqNASDAQ Stock Market requires.

Stockholders Proposals for Nominees.    The Nominating and Corporate Governance Committee will consider written proposals from stockholders for nominees for director. Any such nominations should be submitted to the Nominating and Corporate Governance Committee c/o the Secretary of our Company and should include (at a minimum) the following information: (a) all information relating to such nominee that is required to be disclosed pursuant to Regulation 14A under the Securities Exchange Act of 1934, as amended, or Exchange Act, including such person'sperson’s written consent to being named in the proxy statement as a nominee and to serving as a director if elected; (b) the name(s) and address(es) of the stockholder(s) making the nomination and the number of shares of our common stock which are owned beneficially and of record by such stockholder(s); and (c) appropriate biographical information and a statement as to the qualifications of the nominee, and should be submitted in the time frame described in our Amended and Restated Bylaws and under the caption, “Stockholder Proposals” below.

Process for Identifying and Evaluating Nominees.    The Nominating and Corporate Governance Committee initiates the process for identifying and evaluating nominees to the Board by identifying a slate of candidates who meet the criteria for selection as nominees and have the specific qualities or skills being sought based on

5


input from members of the Board, management and, if the Nominating and Corporate Governance Committee

deems appropriate, a third-party search firm. In addition, we have agreed to take all necessary steps to have one designee of Longitude Venture Partners, L.P., one of our significant stockholders, nominated for election to our Board, subject to compliance with relevant NasdaqNASDAQ Stock Market rules and regulations and approval of the nominee by the Nominating and Corporate Governance Committee. Candidates, including candidates proposed by Longitude Venture Partners, L.P., are evaluated by the Nominating and Corporate Governance Committee on the basis of the factors described above under “Board Membership Criteria.”

With respect to candidates for initial election to the Board, the Nominating and Corporate Governance Committee also reviews biographical information and qualifications and checks the candidates'candidates’ references. Qualified candidates are interviewed by at least one member of the Nominating and Corporate Governance Committee. Serious candidates meet, either in person or by telephone, with all members of the Nominating and Corporate Governance Committee and as many other members of the Board as practicable.

Using the input from interviews and other information obtained, the Nominating and Corporate Governance Committee evaluates which of the prospective candidates is qualified to serve as a director and whether the committee should recommend to the independent members of the Board that the Board nominate, or elect to fill a vacancy with, a prospective candidate. Candidates recommended by the Nominating and Corporate Governance Committee are presented to the independent members of the Board for selection as nominees to be presented for the approval of the stockholders or for election to fill a vacancy. The Nominating and Corporate Governance Committee expects that a similar process will be used to evaluate nominees recommended by stockholders.

Nominees to the Board of Directors for the Annual Meeting.    The nominees for the Annual Meeting were recommended for selection by the Nominating and Corporate Governance Committee and were selected by the independent members of the Board.

BOARD MEETINGS AND COMMITTEES

The Board met fiveeight times during 2009.2010. In addition to the Nominating and Corporate Governance Committee, which is described above, the Board has standing Audit and Compensation Committees. The Audit Committee met fourfive times and the Compensation Committee met twice. The Nominating and Corporate Governance Committee did not meetmet once during 2009.2010. Each member of the Board attended 75% or more of the total number of Board meetings and meetings of Board committees on which such Board member served.

We have a policy of encouraging all directors to attend the annual stockholder meetings. SevenTwo of our directors attended the 20092010 annual stockholder meeting.

Audit Committee.    The Audit Committee currently consists of Joseph L. Turner (Chairman), Patrick G. Enright and David L. Mahoney (Chairman), Joseph C. Cook, Jr. and Patrick G. Enright.Mahoney. The Board has determined that all members of the Audit Committee are independent directors under the rules of the NasdaqNASDAQ Stock Market and each of them is able to read and understand fundamental financial statements. TheIn addition, the Board has determined that David L. Mahoney qualifies as an “Audit Committee financial expert” as defined by the ruleseach member of the SEC.Audit Committee also satisfies the independence requirements of Rule 10A-3(b)(1) of the Exchange Act. The Board has determined that Mr. Enright is independent even though he falls outside the “safe harbor” definition set forth in Rule 10A-3(e)(1)(ii) under the Exchange Act because Longitude Venture Partners, LP and its affiliates own in excess of 10% of our common stock. Among other things, the Board considered Mr. Enright’s history of service and the percentage of common stock held by others, and it determined that he is not an “affiliated person” of our company who would be ineligible to serve on the audit committee.Audit Committee. The Board has determined that each of Messrs. Turner, Mahoney and Enright qualifies as an “Audit Committee financial expert” as defined by Item 407(d)(5) of Regulation S-K of the Securities Act and the Exchange Act. The purpose of the Audit Committee is to oversee ourthe accounting and financial reporting processes and audits of our financial statements.statements audits. The responsibilities of the Audit Committee include appointing and providing for the compensation of the independent registered public registered accounting firm to conduct the annual audit of our accounts, reviewing the scope

and results of

6


the independent audits, reviewing and evaluating internal accounting policies, and approving all professionalallprofessional services to be provided to us by our independent registered public registered accounting firm. The Audit Committee has a written charter, a copy of which is available on our website at www.corcept.com.

Compensation Committee.    The Compensation Committee currently consists of G. Leonard Baker, Jr. (Chairman), Joseph C. Cook, Jr., James A. Harper and David L. Mahoney. The Board has determined that all members of the Compensation Committee are independent directors under the rules of the NasdaqNASDAQ Stock Market. The Compensation Committee administers our benefit plans, reviews and administers all compensation arrangements for executive officers, and establishes and reviews general policies relating to the compensation and benefits of our officers and employees. The Compensation Committee has a written charter, a copy of which is available on our website at www.corcept.com. Pursuant to the Compensation Committee’s charter, the Compensation Committee may delegate its authority and responsibilities as it deems proper to members of the Compensation Committee or to a subcommittee.

BOARD LEADERSHIP STRUCTURE AND ROLE IN RISK OVERSIGHT

Board Leadership Structure.    In accordance with our Amended and Restated Bylaws, our Board appoints our officers, including our Chief Executive Officer. Our Board does not have a policy on whether the role of the Chairman of the Board and Chief Executive Officer should be separate and, if it is to be separate, whether the Chairman of the Board should be selected from the non-employee directors or be an employee and if it is to be combined, whether a lead independent director should be selected. However, our Board is committed to corporate governance practices and values independent board oversight as an essential component of strong corporate performance. For example, fivesix of our seveneight current directors qualify as independent according to the rules and regulations of NASDAQ. In February 2010,March 2011, our Board undertook a review of the independence of each director and considered whether any director has a material relationship with us that could compromise his ability to exercise independent judgment in carrying out his responsibilities. As a result of this review, our Board determined that the following current directors are “independent” under current NasdaqNASDAQ rules:

G. Leonard Baker, Jr.

Joseph C. Cook, Jr.

Patrick G. Enright

James A. Harper

David L. Mahoney

Joseph L. Turner

Currently, we separate the roles of Chief Executive Officer and Chairman of the Board in recognition of the differences between the two roles. The Chief Executive Officer is responsible for setting the strategic direction for our company and the day-to-day leadership and performance of our company, while the Chairman of the Board provides guidance to the Chief Executive Officer and management and sets the agenda for board meetings and presides over meetings of the full Board. Mr.Dr. Belanoff, our Chief Executive Officer, is an employee of our company and is therefore not “independent” under the rules of NasdaqNASDAQ Stock Market. Mr. Wilson, our Chairman of the Board, is an employee of our company and is therefore not “independent” under the rules of NasdaqNASDAQ Stock Market. Our Board believes that the current board leadership structure is appropriate for our company and our stockholders at this time.

Risk Oversight.    The Board oversees our company’s risk exposures and risk management of various parts of the business, including appropriate guidelines and policies to minimize business risks and major financial risks and the steps management has undertaken to control them. In its risk oversight role, the Board reviews our strategic plan at least annually, which includes an assessment of potential risks facing us. While the Board has the ultimate oversight responsibility for the risk management process, various committees of the Board also have responsibility for risk management. Our Audit Committee is responsible for overseeing management of our risks

relating to accounting matters, financial reporting and SEC compliance. Our Compensation Committee is responsible for overseeing the management of risks relating to our company’s executive compensation plans and

7


arrangements. In addition, in setting compensation, the Compensation Committee strives to create incentives that do not encourage risk-taking behavior that is inconsistent with our company’s business strategy. Our Nominating and Corporate Governance Committee is responsible for overseeing management of our risks associated with the independence of our Board and potential conflicts of interest. Each committee regularly reports to the full board of directors.

COMMUNICATIONS WITH DIRECTORS

Stockholders or other interested parties may communicate with any director or committee of our Board by writing to them c/o Secretary, Corcept Therapeutics Incorporated, 149 Commonwealth Drive, Menlo Park, California 94025. Comments or questions regarding our accounting, internal controls or auditing matters will be referred to members of the Audit Committee. Comments or questions regarding the nomination of directors and other corporate governance matters will be referred to members of the Nominating and Corporate Governance Committee.

CODE OF ETHICS

We have adopted a code of ethics that applies to all of our officers and employees, including our principal executive officer and our principal financial officer, a copy of which is available on our website at www.corcept.com. We will also deliver a copy of our code of ethics to any stockholder, without charge, upon written request to Corcept Therapeutics Incorporated, 149 Commonwealth Drive, Menlo Park, California 94025, Attention: Secretary, or upon oral request by calling (650) 327-3270.

COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

The current members of our Compensation Committee are G. Leonard Baker, Jr., Joseph C. Cook, Jr., James A. Harper and David L. Mahoney. None of the members of our Compensation Committee is currently, or has been, an officer or employee of our company. No interlocking relationship exists, or in the past year has existed, between any member of our Compensation Committee and any member of any other company’s board of directors or compensation committee. Messrs Baker, Cook and Mahoney each participated in the 2010 Warrant Financing as described in “Certain Relationships and Related Transactions” below, either in an individual capacity or through related entities.

INFORMATION CONCERNING EXECUTIVE OFFICERS

The names ofInformation relating to our executive officers their ages as of April 30, 2010 and certain other information about them are set forth below:

Name

Age

Position

Joseph K. Belanoff, M.D.

52Chief Executive Officer and Director

Robert L. Roe, M.D.

69President and Secretary

Caroline M. Loewy

44Chief Financial Officer

Anne M. LeDoux

62Vice President, Controller and Chief Accounting Officer

Joseph K. Belanoff, M.D. Biographical information regarding Dr. Belanoff is set forth under “Nominees to Board of Directors.”

Robert L. Roe, M.D. joined our company as President in October 2001. Dr. Roe has spent more than 30 years inincorporated by reference herein from the pharmaceutical and biotechnology industries. From 1999 to 2001, he served as President and Chief Executive Officer of Allergenics, Inc. From 1996 to 1999, he was Executive Vice President, Chief Operating Officer and a director of Cytel Corporation. From 1995 to 1996, he was Executive Vice President, Chief

8


Operating Officer and a director of Chugai Biopharmaceuticals, Inc. From 1992 to 1995, Dr. Roe served as Presidentsection captioned “Executive Officers of the Development Research Division and Senior Vice PresidentCompany” contained in Part I, Item 1 of Syntex Corporation. Dr. Roe received his B.A. from Stanford University and his M.D. from the University of California, San Francisco.

Caroline M. Loewy joined our company as Chief Financial Officer in November 2008. From 2006-2008, Ms. Loewy served as Chief Financial Officer of Poniard Pharmaceuticals, a publicly traded biopharmaceutical company. From 2004-2006 she acted as an independent consultant to a variety of biopharmaceutical companies advisingAnnual Report on corporate strategy, business development, and financing. Ms. Loewy spent 14 years in equity research and corporate finance. From 2000-2004 she was an Executive Director in biotechnology equity research at Morgan Stanley, providing fundamental analysis and recommendations to investors, as well as strategic advisory services to corporate clients. She was also a Managing Director in biotechnology equity research at Prudential Securities and held positions in corporate finance at BankAmerica. Ms. Loewy holds a BA degree from the University of California, Berkeley, and an MBA/MS degree from Carnegie Mellon University.

Anne M. LeDoux joined our company as Controller in 2004 and was promoted to the position of Vice President, Controller and Chief Accounting Officer in April 2007. Ms. LeDoux has over 15 years of financial and accounting management experience with public pharmaceutical and biotechnology companies. Prior to joining our company in 2004, Ms. LeDoux served in various financial positions at Aviron, Roche Biosciences and Syntex Corporation. She was also Vice President and Chief Financial Officer at the Northern California Health Center and Vice President, FinanceForm 10-K for the Children’s Hospital of San Francisco. Ms. LeDoux is a Certified Public Accountant and has over 13 years of experience in public accounting, primarily at Coopers and Lybrand. Ms. LeDoux received her Bachelor of Arts degree in Business fromyear ended December 31, 2010, filed with the University of Massachusetts and a law degree from Western New England College, School of Law.SEC on March 15, 2011.

9


SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

The following table sets forth information regarding ownership of our common stock as of April 21, 201010, 2011 or earlier date for information based on filings with the SEC by (a) each person known to us to own more than 5% of the outstanding shares of our common stock, (b) our directors, (c) our Chief Executive Officer and each other executive officer named in the compensation tables appearing later in this proxy statement and (d) all directors

and executive officers as a group. The information in this table is based solely on statements in filings with the SEC or other information we believe to be reliable. Percentage of ownership is based on 67,031,36283,968,540 shares of common stock outstanding as of April 21, 2010.10, 2011. Beneficial ownership is determined in accordance with the rules of the SEC, and includes voting and investment power with respect to the shares. Shares of common stock subject to outstanding options and warrants exercisable within 60 days of April 21, 201010, 2011 are deemed outstanding for computing the percentage of ownership of the person holding such options or warrants, but are not deemed outstanding for computing the percentage of any other person.

 

Name of Beneficial Owner(1)

  Number of Shares
Beneficially  Owned(2)
  Percentage of Shares
Beneficially Owned
 

5% Stockholders

    

Longitude Venture Partners, LP and affiliated entities and individuals(3)

  15,012,908  21.4

Sutter Hill Ventures and affiliated entities and individuals(4)

  13,618,891  19.8

Alta Partners, II, Inc. and affiliated entity(5)

  6,316,212  9.3

Federated Funds(6)

  4,755,247  7.0

Ingalls & Snyder, LLC and affiliated entities and individuals(7)

  5,362,371  7.9

Directors and Named Executive Officers

    

Patrick G. Enright(3)

  15,012,908  21.4

G. Leonard Baker, Jr.(8)

  9,472,846  13.9

Joseph K. Belanoff(9)

  3,701,725  5.4

Joseph C. Cook, Jr.(10)

  3,481,521  5.2

James N. Wilson(11)

  3,286,652  4.9

David L. Mahoney(12)

  1,412,852  2.1

Robert L. Roe(13)

  1,021,409  1.5

Caroline M. Loewy(14)

  300,009  *  

Anne M. LeDoux(15)

  209,442  *  

James A. Harper(16)

  187,400  *  
     

All directors and executive officers as a group (10 persons)(17)

  38,086,764  50.9
     

Name of Beneficial Owner(1)

  Number of Shares
Beneficially  Owned(2)
   Percentage of Shares
Beneficially Owned
 

5% Stockholders

    

Longitude Venture Partners, LP and affiliated entities and individuals(3)

   15,807,909     18.1

Sutter Hill Ventures and affiliated entities and individuals(4)

   13,646,391     15.9

Federated Investors, Inc. and affiliated entities(5)

   5,505,247     6.5

Ingalls & Snyder, LLC and affiliated entities(6)

   4,786,313     5.7

Directors and Named Executive Officers

    

Patrick G. Enright(3)

   15,807,909     18.1

G. Leonard Baker, Jr.(7)

   9,500,346     11.1

Joseph K. Belanoff(8)

   4,035,037     4.7

James N. Wilson(9)

   3,383,941     4.0

Joseph C. Cook, Jr.(10)

   3,016,515     3.6

David L. Mahoney(11)

   1,458,685     1.7

Robert L. Roe(12)

   1,039,126     1.2

Caroline M. Loewy(13)

   500,016     *  

Anne M. LeDoux(14)

   267,710     *  

James A. Harper(15)

   214,900     *  

Joseph L. Turner(16)

   8,571     *  

Steven Lo(17)

        *  
       

All directors and executive officers as a group (12 persons)(18)

   39,232,756     42.2
       

 

*LessLess than 1% of our outstanding common stock.

 

(1)

Unless otherwise indicated, the address of each of the named individuals is c/o Corcept Therapeutics, 149 Commonwealth Drive, Menlo Park, California 94025.

 

(2)

Beneficial ownership of shares is determined in accordance with the rules of the SEC and generally includes any shares over which a person exercises sole or shared voting or investment power, or of which a person has the right to acquire ownership within 60 days after April 21, 2010.10, 2011. Except as otherwise noted, each person or entity has sole voting and investment power with respect to the shares shown.

 

(3)

IncludesConsists of (a) 11,670,77012,406,033 shares held by Longitude Venture Partners, LP, and 3,091,479 shares that may be acquired by that entity within 60 days of April 21, 201010, 2011 pursuant to warrants, (b) 156,159170,896 shares held by Longitude Capital Associates, L.P. and 26,583 shares that may be acquired by that entity within 60 days of April 21, 201010, 2011 pursuant to warrants and (c) 67,917112,918 shares that may be acquired by

10


Patrick Enright within 60 days of April 21, 201010, 2011 pursuant to options. Juliet Tammenoms Bakker and Mr. Enright may be deemed to have shared voting and investment power over the shares held by Longitude Venture Partners, LP, and Longitude Capital Associates, L.P. Each of these individuals disclaims beneficial ownership of all such shares, except to the extent of his or her pecuniary interest therein. The address for Longitude Capital is 800 El Camino Real, Suite 220, Menlo Park, California 94025. Mr. Enright is a member of our Board of Directors and a managing member of Longitude Capital Partners, LLC, the general partner of each of Longitude Venture Partners, LP, and Longitude Capital Associates, L.P.

(4)

Consists of: (a) 5,525,017 shares held by Sutter Hill Ventures, aA California Limited Partnership, which is referred to as Sutter Hill Ventures, and 707,752 shares that may be acquired by that entity within 60 days of April 21, 201010, 2011 pursuant to warrants, (b) 29,273 shares held by Sutter Hill Entrepreneurs Fund (AI), L.P., which is referred to as SHAI, (c) 74,113 shares held by Sutter Hill Entrepreneurs Fund (QP), L.P., which is referred to as SHQP, (d) 205,439 shares of common stock held by G. Leonard Baker, Jr., one of our directors, (e) 1,180,231 shares held by Mr. Baker, as Trustee of The Baker Revocable Trust, and 228,765 shares that may be acquired by that trust within 60 days of April 21, 201010, 2011 pursuant to warrants, (f) 839,059 shares held by Saunders Holdings, L.P. of which Mr. Baker is a general partner, and 115,015 shares that may be acquired by that entity within 60 days of April 21, 201010, 2011 pursuant to warrants, (g) 379,733 shares held by the Sutter Hill Ventures Profit Sharing Plan, for the benefit of Mr. Baker, and 98,449 shares that may be acquired by that entity within 60 days of April 21, 201010, 2011 pursuant to a warrant, (h) 90,000117,500 shares that may be acquired by Mr. Baker within 60 days of April 21, 201010, 2011 pursuant to options and (i) 3,663,260 shares held by individuals other than Mr. Baker who are affiliated with Sutter Hill Ventures or entities affiliated with such individuals, and 482,785 shares that may be acquired by such individuals and entities within 60 days of April 21, 201010, 2011 pursuant to warrants. Mr. Baker may be deemed to have shared voting and investment power with respect to the shares and warrants held by The Baker Revocable Trust and Saunders Holdings, L.P. Mr. Baker, Sutter Hill Ventures, SHAI and SHQP do not have any voting or investment power with respect to the shares held by individuals affiliated with Sutter Hill Ventures and entities affiliated with such individuals referenced under part (i) of this note. Mr. Baker, David L. Anderson, William H. Younger, Jr., Tench Coxe, Gregory P. Sands, James C. Gaither, James N. White, Jeffrey W. Bird, David E. Sweet, Andrew T. Sheehan and Michael L. Speiser, referred to collectively as the Sutter Hill Principals, may be deemed to have shared voting and investment power with respect to the shares held by Sutter Hill Ventures, SHAI and SHQP. As a result of the shared voting and investmentdispositive powers referenced herein, Messrs. Baker, Anderson, Younger, Coxe, Sands, Gaither, White, Bird, Sweet, Sheehan and Speiser may each be deemed to beneficially own the shares held by Sutter Hill Ventures, SHAI and SHQP. Each of these individuals disclaims beneficial ownership of all holdings reflected herein, except to the extent of his individual pecuniary interest therein. The address for Sutter Hill Ventures and affiliates is 755 Page Mill Road, Suite A-200, Palo Alto, CA 94304. Mr. Baker, a member of our Board of Directors, is also a managing director of the general partner of Sutter Hill Ventures.

 

(5)

Consists of:Includes (a) 5,484,0633,776,225 shares beneficially held by Alta BioPharma Partners II, L.P.registered investment companies and separate accounts advised by subsidiaries of Federated Investors, Inc., or Federated, that have been delegated the power to direct investments and 640,996power to vote the securities by the registered investment companies’ board of trustees or directors and by the separate accounts’ principals and (b) 979,022 shares that may be acquired by that entitysuch entities within 60 days of April 21,December 31, 2010 pursuant to warrants, and (b) 180,204 shares heldwarrants. The foregoing beneficial ownership information is based on information obtained from the Amendment No. 1 to Form 13G filed by Alta Embarcadero BioPharma Partners II, LLC, and 10,949 shares that may be acquired by that entity within 60 days of April 21, 2010 pursuant to warrants.Alta Partners II,Federated Investors, Inc. provides investment advisory services to several venture capital funds including Alta BioPharma Partners II, L.P. and Alta Embarcadero BioPharma Partners II, LLC. The managing directors of Alta BioPharma Partners II, L.P. and the managers of Alta Embarcadero BioPharma Partners II, LLC exercise sole voting and investment power with respect to its holdings as of December 31, 2010. In addition, we are aware that entities affiliated with Federated purchased 750,000 shares owned by such funds. Certain principals of Alta Partners II, Inc. are managing directors of Alta BioPharma Management II, LLC (whichin our underwritten public offering on January 26, 2011. Federated is the general partnerparent holding company of Alta BioPharma Partners II, L.P.)Federated Equity Management Company of Pennsylvania and Federated Global Investment Management Corp., collectively referred to herein as the Investment Advisers, which act as investment advisers to registered investment companies and managersseparate accounts that own shares of Alta Embarcadero BioPharma Partners II, LLC. As managing directors and managersour common stock. The Investment Advisers are wholly owned subsidiaries of such entities, they may be deemed to share voting and investment power for the shares held by the funds. The principals of Alta Partners II,FII Holdings, Inc., Farah Champsi, Jean Deleage,which is wholly owned subsidiary of Federated. All of Federated’s outstanding voting stock is held in the Voting Shares Irrevocable Trust, or the Trust, for which John F. Donahue, Rhodora J. Donahue and Edward Penhoet, disclaimJ. Christopher Donahue act as trustees, collectively referred to herein as the Trustees. The Trustees exercise collective voting control over Federated. Each of Federated, the Trust and the Trustees disclaims beneficial ownership of all such shares held by the foregoing funds,holdings reflected herein, except to the extent of their proportionatehis individual pecuniary interestsinterest therein. TheFederated’s address of Alta Partners II, Inc. is One Embarcadero Center, Suite 3700, San Francisco, California 94111.Federated Investors Tower, Pittsburgh, PA 15222-3779.

 

((6)6)

Consists of (a) 3,075,523 shares beneficially held by Federated Kaufmann Fund, or FKF, and 797,358 shares that may be acquired by that entity within 60 days of April 21, 2010 pursuant to a warrant, (b) 467,262 shares beneficially held by Federated Kaufmann Small Cap Fund, or FKSCF, and 121,142 shares that may be acquired by that entity within 60 days of April 21, 2010 pursuant to a warrant, (c) 166,377 shares beneficially held by American Skandia Trust, Federated Aggressive Growth Portfolio, or ASTAG, and 43,135 shares that may be acquired by that entity within 60 days of April 21, 2010 pursuant to a warrant and (d) 67,063 shares beneficially held by Federated Kaufmann Fund II, or FKFII, and 17,387 shares that may be acquired by that entity within 60 days of April 21, 2010 pursuant to a warrant. Each of FKF and FKSCF is a portfolio of Federated Equity Funds, an investment company registered under the Investment Company Act of 1940, as amended, or Investment Company Act. American Skandia Trust, Federated Aggressive Growth Portfolio, or ASTAG, is a portfolio of Advanced Series Trust, an investment company registered under the Investment Company Act. ASTAG’s investment advisors are Prudential Investments LLC and AST Investment Services, Inc., which have delegated daily management of the fund’s assets to Federated Equity Management Company of Pennsylvania, or FEMCPA, as sub-advisor. Federated Kaufmann Fund II, or FKFII, is a portfolio of Federated Insurance Series, an investment company registered under the Investment Company Act. We refer to FKF, FKSCF, ASTAG and FKFII collectively as the Federated Funds. The parent holding company of the advisors of each Federated Fund is Federated Investors Inc., or FII. The advisor of each Federated Fund is FEMCPA, which has delegated daily management of the fund’s assets to Federated Global Investment Management Corp., or FGIMC, as subadvisor. In the case of ASTAG, FEMCPA as sub-advisor, has delegated daily management of the fund’s assets to FGIMIC as sub-sub-advisor. While the officers and directors of FEMCPA have dispositive power over the portfolio securities of each of the Federated Funds, they customarily delegate this dispositive power, and therefore the day-to-day dispositive decisions are made by the portfolio managers of each of Federated Funds. The portfolio managers disclaim any beneficial ownership of these securities. With respect to voting power, each of the Federated Funds has delegated the authority to vote proxies to FEMCPA. FEMCPA has established a Proxy Voting Committee to cast proxy votes on behalf of each of

11


the Federated Funds in accordance with proxy voting policies and procedures approved by the applicable Federated Fund. Securities are held of record by Playback & Co., Boathorn & Co., Hare & Co. and Turnseal & Co. on behalf of FKF, FKSCF, ASTAG and FKFII, respectively. FKF, FKSCF and FKFII’s address is 4000 Ericsson Drive, Warrendale, Pennsylvania 15086-7561. ASTAG’s address is Gateway Center Three, 100 Mulberry Street, Newark, NJ 07102.

(7)

Consists ofIncludes (a) 2,700,000 shares held by Ingalls & Snyder Value Partners, L.P., or Ingalls,ISVP, and 700,000 shares that may be acquired by IngallsISVP within 60 days of AprilJanuary 21, 20102011 pursuant to a warrant and (b) 98,3131,386,313 shares held by Ingalls & Snyder LLC, (c) 1,350,000or Ingalls for the benefit of investment advisory clients other than ISVP. Information regarding the holdings of Ingalls and ISVP is based on information obtained from Amendment No. 2 to Form 13G filed by Ingalls with respect to its holdings as of January 21, 2011. ISVP is an investment partnership managed under an investment advisory contract by Ingalls, a registered broker dealer and a registered investment advisor. Ingalls holds investment authority but not voting authority over shares held by its investment advisory clients. Mr. Thomas O. Boucher, Jr., a Managing Director of Ingalls, and Mr. Robert L. Gipson and 350,000 shares that may be acquired by Mr. Gipson within 60 days of April 21, 2010 pursuant to a warrant and (d) 130,281 shares held by Thomas O. Boucher, Jr. and 33,777 shares that may be acquired by Mr. Boucher within 60 days of April 21, 2010 pursuant to a warrant. Ingalls & Snyder LLC, the investment advisorAdam Janovic, Senior Directors of Ingalls, and Mr. Boucher, Mr. Gipson, and Adam Janovic, each aare the general partnerpartners of Ingalls,ISVP and share investment power over the shares held by Ingalls. Messrs. Boucher, Gipson and Janovic share voting power over the shares held by Ingalls.ISVP. Each of these individuals disclaims beneficial ownership of all such shares, except to the extent of his individual pecuniary interest therein. The address for Ingalls & Snyder LLCand ISVP is 61 Broadway, New York, New York 10006.

 

(8)(7)

Mr. Baker’s beneficial holdings include all shares referenced in footnote (4) other than the shares and warrants referenced under part (i) of footnote (4).

 

(9)(8)

Includes (a) 1,270,842 shares that may be acquired by Dr. Belanoff within 60 days of April 10, 2011 pursuant to options, (b) 300,000 shares held as custodian for Edward G. Belanoff and (c) 300,000 shares held as custodian for Julia E. Belanoff under the California Uniform Transfers to Minors Act over which Dr. Belanoff has voting control, (b) 300,000 shares held as custodian for Edward G. Belanoff and (c) 937,530control.

(9)

Includes (a) 400,004 shares that may be acquired by Dr. BelanoffMr. Wilson within 60 days of April 21, 201010, 2011 pursuant to options.options, (b) 2,034,511 shares held by the James N. Wilson and Pamela D. Wilson Trust, (c) 931,774 shares held by the James and Pamela Wilson Family Partners and (d) 17,652 shares that may be acquired by the James and Pamela Wilson Family Partners within 60 days of April 10, 2011 pursuant to a warrant. Mr. Wilson has voting power over the shares held by the James N. Wilson and Pamela D. Wilson Trust and the James and Pamela Wilson Family Partners pursuant to voting agreements. Mr. Wilson disclaims beneficial ownership of all of such shares, except to the extent of his pecuniary interest therein.

(10)

Consists of (a) 1,130,0001,184,743 shares and 193,258 shares that may be acquired within 60 days of April 10, 2011 pursuant to warrants that are held jointly by Joseph C. Cook, Jr. and Judith Cook, (b) 534,762 shares held by Farview Management, Co. L.P., a Texas limited partnership, and 14,402 shares that may be acquired by that entity within 60 days of April 21, 201010, 2011 pursuant to a warrant, (b) 1,082,011 shares and 193,258 shares that may be acquired within 60 days of April 21, 2010 pursuant to warrants that are held jointly by Joseph C. Cook, Jr. and Judith Cook (c) 476,016 shares held by the Joseph C. Cook, Jr., IRA Rollover, or Cook IRA, and 86,839 shares that may be acquired by the Cook IRA within 60 days of April 21, 201010, 2011 pursuant to a warrant, (d) 350,000 shares held by the Judith E. and Joseph C. Cook, Jr. Foundation, Inc. and 13,995 shares that may be acquired by that entity within 60 days of April 21, 201010, 2011 pursuant to a warrant and (e) 135,000162,500 shares that may be acquired by Mr. Cook within 60 days of April 21, 201010, 2011 pursuant to options. Mr. Cook and Judith E. Cook may be deemed to have shared voting and investment power over the shares held by the Cook Foundation. Each of these individuals disclaims beneficial ownership of all such shares, except to the extent of his or her pecuniary interest therein. Mr. Cook and Judith E. Cook may be deemed to have shared voting and investment power over the shares held in joint name. Mr. Cook is a member of our Board of Directors.

 

(11)

Includes (a) 242,715 shares that may be acquired by Mr. Wilson within 60 days of April 21, 2010 pursuant to options, (b) 2,074,511 shares held by the James N. Wilson and Pamela D. Wilson Trust, (c) 951,774 shares held by the James and Pamela Wilson Family Partners and (d) 17,652 shares that may be acquired by the James and Pamela Wilson Family Partners within 60 days of April 21, 2010 pursuant to a warrant. Mr. Wilson has voting power over the shares held by the James N. Wilson and Pamela D. Wilson Trust and the James and Pamela Wilson Family Partners pursuant to voting agreements. Mr. Wilson disclaims beneficial ownership of all of such shares, except to the extent of his pecuniary interest therein.

(12)

Includes (a) 1,118,0621,018,062 shares held by the David L. Mahoney and Winnifred C. Ellis 1998 Family Trust, and 114,790 shares that may be acquired by the Trust within 60 days of April 21, 201010, 2011 pursuant to warrants, (b) 100,000 shares held by the Black Dog Private Foundation, of which Mr. Mahoney is the president and (b) 180,000(c) 225,833 shares that may be acquired by Mr. Mahoney within 60 days of April 21, 201010, 2011 pursuant to options. Mr. Mahoney is a member of our BoardBoard.

(12)

Includes 1,000,236 shares that may be acquired by Dr. Roe within 60 days of Directors.April 10, 2011 pursuant to options.

 

(13)

Includes 872,519 shares that may be acquired by Mr. Roe within 60 daysConsists of April 21, 2010 pursuant to options.

(14)

Includes 300,009500,016 shares that may be acquired by Ms. Loewy within 60 days of April 21, 201010, 2011 pursuant to options.an option.

 

(15)(14)

Includes 209,442Consists of 267,710 shares that may be acquired by Ms. LeDoux within 60 days of April 21, 201010, 2011 pursuant to options.

 

(16)(15)

Includes (a) 25,000 shares held by the James A. Harper 2008 Annuity Trust over which Mr. Harper is Trustee and has voting power, (b) 25,000 shares held by the Zo P. Harper 2008 Annuity Trust over which Mr. Harper’s spouse, Zo P. Harper, is Trustee and has voting power and (c) 120,000147,700 shares that may be acquired by Mr. Harper within 60 days of April 21, 201010, 2011 pursuant to options. Mr. Harper disclaims beneficial ownership of all of such shares, except to the extent of his pecuniary interest therein.

 

(16)

Mr. Turner’s holdings include 8,571 shares that may be acquired by Mr. Turner within 60 days of April 10, 2011 pursuant to an option.

(17)

Mr. Lo has no direct holdings as of April 10, 2011, and no options exercisable within 60 days of April 10, 2011.

(18)

Total number of shares includes common stock held by directors, executive officers and entities affiliated with directors and executive officers. See footnotes 1 through 4 and 8 though 167 through 17 above.

CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

As a matter of policy, all related-party transactions between us and any of our officers, directors, or principal stockholders, are approved by our Audit Committee or a majority of the independent and disinterested members of our Board, are on terms no less favorable to us than could be obtained from unaffiliated third parties and are in connection with bona fide business purposes.

Paperboy Note Receivable. On February 6, 2009, we collected a note receivable of $6.0 million from Paperboy Ventures, LLC that had been issued in March 2008 in connection with a private placement of our

12


common stock and warrants. The note was collected in full, including all accrued interest to that date and expenses associated with the note. Allen Andersson, the chairman of Paperboy Ventures, LLC, was a member of our Board from June 2007 to June 2009.

October 2009 Financing.2011 Public Offering.    On October 12, 2009,January 26, 2011, we entered into a definitive agreement with certain accredited investors for the private placement of 12,596,475sold 11.5 million shares of our common stock and warrants to purchase 4,408,773 shares of our common stock, which we refer to as the October 2009 Financing. The securities were soldin an underwritten public offering at a purchase price to the public of $1.43$3.90 per unit, which consisted of one share of common stock and a warrant to purchase 0.35 shares of common stock. The warrants have a three-year term and an exercise price of $1.66 per share. The October 2009 Financing, which closed on October 16, 2009, generatedfor aggregate net proceeds of approximately $17.3$41.9 million after deducting coststhe underwriters’ discount and commissions and other expenses of issuance.

Investors participating in the October 2009 Financing included funds managed by or investors affiliated with existing stockholders,offering. Longitude Venture Partners, L.P., Sutter Hill Ventures and Alta Partners. The investors also included trusts and other entities related to membersLP purchased 750,000 shares in this transaction (approximately 6.5% of our Board of Directors, including G. Leonard Baker, Jr., Joseph C. Cook,the shares sold). Patrick G. Enright, David L. Mahoney and Edward E. Penhoet, Ph.D., who wasis a member of our Boardboard of Directors at the time of the October 2009 Financing. Mr. Enrightdirectors, is a managing member of Longitude Capital Partners, which isLLC, the general partner of Longitude Venture Partners, L.P. Mr. Baker is a partner and managing director of Sutter Hill Ventures. Dr. Penhoet is a director of Alta Partners. The participation in the October 2009 Financing by these investors, to whom we refer collectively as the October 2009 Related Parties, are set forth in the table below:

Name of October 2009 Related Party

  Number of
Shares of
Common
Stock
  Number of
Shares
Underlying
Warrants
  Aggregate
Amount
Invested

Longitude Ventures Partners, L.P. and affiliated entity(1)

  2,447,553  856,644  $3,500,001

Sutter Hill Ventures, L.P. and affiliated entities(2)

  1,883,556  659,245  $2,693,485

Joseph C. Cook, Jr.(3)

  384,617  134,617  $550,002

Alta Biopharma Partners II, L.P. and affiliated entity(4)

  349,651  122,378  $500,001

David L. Mahoney(5)

  139,861  48,952  $200,001

(1)

Consists of (a) 2,399,459 shares of common stock and a warrant to purchase 839,811 shares of common stock purchased by Longitude Venture Partners, L.P. and (b) 48,094 shares of common stock and a warrant to purchase 16,833 shares of common stock purchased by Longitude Capital Associates. Patrick Enright, a member of our Board is a managing member of Longitude Capital Partners, the general partner of Longitude Venture Partners, L.P. and Longitude Capital Associates.

(2)

Consists of (a) 878,722 shares of common stock and a warrant to purchase 307,553 shares of common stock purchased by Sutter Hill Ventures, L.P., (b) 281,284 shares of common stock and a warrant to purchase 98,449 shares of common stock purchased by Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO G. Leonard Baker, Jr., (c) 133,688 shares of common stock and a warrant to purchase 46,791 shares of common stock purchased by Saunders Holdings, L.P., (d) 202,479 shares of common stock and a warrant to purchase 70,867 shares of common stock purchased by Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO Tench Coxe, (e) 158,551 shares of common stock and a warrant to purchase 55,493 shares of common stock purchased by Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO William H. Younger, Jr., (f) 149,432 shares of common stock and a warrant to purchase 52,301 shares of common stock purchased by Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO David L. Anderson, (g) 24,105 shares of common stock and a warrant to purchase 8,437 shares of common stock purchased by Gregory P. and Sarah J.D. Sands Trust under agreement dated 2/24/99, (h) 23,154 shares of common stock and a warrant to purchase 8,104 shares of common stock purchased by The White Family Trust U/A/D 4/3/97, (i) 20,850 shares of common stock and a warrant to purchase 7,298 shares of common stock purchased by Jeffrey W. and Christina R. Bird Trust under agreement dated 10/31/00, (j) 8,265 shares of common stock and a warrant to purchase 2,893 shares of common stock purchased by Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO David E. Sweet (Rollover) and (k) 3,026 shares of common stock and a warrant to purchase 1,059 shares of common stock purchased by Sheehan 2003 Trust. G. Leonard Baker, Jr., a member of our Board, is a partner and managing director of Sutter Hill Ventures, L.P. and may be deemed to have beneficial ownership of the shares discussed in parts (a) through (c) of this footnote. See the discussion in “Security Ownership of Certain Beneficial Owners and Management” for a discussion regarding the beneficial ownership of the Sutter Hill Principals.

(3)

Consists of (a) 209,791 shares of common stock and a warrant to purchase 73,427 shares of common stock purchased by Joseph C. Cook Jr. and Judith Cook, as Tenants in Common, and (b) 174,826 shares of common stock and a warrant to purchase 61,190 shares of common stock purchased by the Joseph C. Cook, Jr. Rollover IRA. Joseph C. Cook, Jr., is a member of our Board.

13


(4)

Consists of (a) 337,245 shares of common stock and a warrant to purchase 118,036 shares of common stock purchased by Alta Biopharma Partners II, L.P. and (b) 12,406 shares of common stock and a warrant to purchase 4,342 shares of common stock purchased by Alta Embarcadero Biopharma Partners II, LLC. Edward E. Penhoet, Ph.D., who was a member of our Board at the time of the October 2009 Financing, is a director and a limited partner of Alta Biopharma Partners II, L.P. and a member of Alta Embarcadero Biopharma Partners II, LLC.

(5)

Consists of shares and warrants purchased by The David L. Mahoney and Winnifred C. Ellis 1998 Family Trust, of which David L. Mahoney, a member of our Board, is a trustee.

In connection with the October 2009 Financing, we entered into a Registration Rights Agreement, or the October 2009 Registration Rights Agreement, with the investors in the October 2009 Financing, including the October 2009 Related Parties. Pursuant to the October 2009 Registration Rights Agreement, we agreed to prepare and file a registration statement with the SEC to register the resale of the shares, the shares of common stock issuable upon exercise of the warrants and any shares of common stock issued as a dividend or other distribution with respect to the shares or shares underlying the warrants. This registration statement was filed on November 16, 2009 and declared effective by the SEC on January 26, 2010. We also agreed, among other things, to indemnify the selling stockholders under the registration statement, including the October 2009 Related Parties, from certain liabilities and to pay all fees and expenses (excluding underwriting discounts and selling commissions and all legal fees of any selling stockholder) incident to our obligations under the October 2009 Registration Rights Agreement.

Preemptive Rights.    In addition, in connection with the October 2009 Financing, we granted each investor preemptive rights to purchase its pro rata share of all common stock or common stock equivalents, that we may, from time to time, propose to sell and issue, other than certain excluded securities, commencing from and after October 16, 2009 until the unblinded data from our Phase 3 Cushing’s Syndrome trial is generally available to and known by the public.LP.

2010 Warrant Financing.    On April 21, 2010 certain existing investors, who had participated in the October 2009 Financing, including the related parties below, who had participated in a private placement in October 2009, which we refer to collectively as the WarrantOctober 2009 Financing, Related Parties, exercised the warrants they purchased in the October 2009 Financing. For purposes of this section, we refer to this transaction as the 2010 Warrant Financing. The exercise price of these warrants was $1.66 per share, resulting in gross proceeds to us of approximately $7.1 million. Conditioned on the investors’ agreement to exercise their existing warrants, on April 21, 2010, we entered into a definitive agreement with such investors to raise approximately $0.5 million in additional gross proceeds in a private placement through the sale of warrants to purchase an aggregate of approximately 4.3 million shares of the our common stock. The warrants were sold at $0.125 per share of common stock underlying these warrants. The warrants have a three-year term and a per share exercise price of $2.96. The closing of the 2010 Warrant Financing occurred on April 21, 2010.

In connection with the 2010 Warrant Financing, the Warrant Financing Related Partiesfollowing related parties purchased the shares of common stock and warrants at the aggregate purchase prices set forth below:

 

Name of Warrant Financing Related Party

  Number of Shares
of Common Stock
Purchased Upon
Exercise of
Warrants
  Number of
Shares
Underlying
New
Warrants
  Aggregate
Amount
Invested

Name of Related Party

  Number of Shares
of Common Stock
Purchased Upon
Exercise  of
Warrants
   Number of
Shares
Underlying
New
Warrants
   Aggregate
Amount
Invested
 

Longitude Ventures Partners, L.P. and affiliated entity(1)

  856,644  856,644  $1,529,110   856,644     856,644    $1,529,110  

Sutter Hill Ventures, L.P. and affiliated entities(2)

  659,245  659,245  $1,176,752

Sutter Hill Ventures, L.P. and affiliated entity(2)

   659,245     659,245    $1,176,752  

Joseph C. Cook, Jr.(3)

  134,617  134,617  $240,291   134,617     134,617    $240,291  

David L. Mahoney(4)

  48,952  48,952  $87,379   48,952     48,952    $87,379  

 

(1)

Consists of (a) 839,811 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 839,811 shares of common stock purchased by Longitude Venture Partners, L.P. and (b) 16,833 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 16,833 shares of common stock purchased by Longitude Capital Associates. Patrick Enright, a member of our Board is a managing member of Longitude Capital Partners, the general partner of Longitude Venture Partners, L.P. and Longitude Capital Associates.

 

14


(2)

Consists of (a) 307,553 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 307,553 shares of common stock purchased by Sutter Hill Ventures, L.P., (b) 98,449 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 98,449 shares of common stock purchased by Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO G. Leonard Baker, Jr., (c) 46,791 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 46,791 shares of common stock purchased by Saunders Holdings, L.P., of which Mr. Baker is a general partner, (d) 70,867 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 70,867 shares of common stock purchased by Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO Tench Coxe, (e) 55,493 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 55,493 shares of common stock purchased by Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO William H. Younger, Jr., (f) 52,301 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 52,301 shares of common stock purchased by Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO David L. Anderson, (g) 8,437 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 8,437 shares of common stock purchased by Gregory P. and Sarah J.D. Sands Trust under agreement dated 2/24/99, (h) 8,104 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 8,104 shares of common stock purchased by The White Family Trust U/A/D 4/3/97, (i) 7,298 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 7,298 shares of common stock purchased by Jeffrey W. and Christina R. Bird Trust under agreement dated 10/31/00, (j) 2,893 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 2,893 shares of common stock purchased by Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO David E. Sweet (Rollover) and (k) 1,059 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 1,059 shares of common stock purchased by Sheehan 2003 Trust. G. Leonard Baker, Jr., a member of our Board, is a partner and managing director of Sutter Hill Ventures, L.P. and may be deemed to have beneficial ownership of the shares discussed in parts (a) through (c) of this footnote. See the discussion in “Security Ownership of Certain Beneficial Owners and Management” for a discussion regarding the beneficial ownership of the Sutter Hill Principals.

 

(3)

Consists of (a) 73,427 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 73,427 shares of common stock purchased by Joseph C. Cook Jr. and Judith Cook, as Tenants in Common, and (b) 61,190 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 61,190 shares of common stock purchased by the Joseph C. Cook, Jr. IRA, each of which are affiliated with Joseph C. Cook, Jr., a member of our Board.

 

(4)

Consists of 48,952 shares of common stock issued upon the exercise of a warrant and a warrant to purchase 48,952 shares of common stock purchased by The David L. Mahoney and Winnifred C. Ellis 1998 Family Trust, of which David L. Mahoney, a member of our Board, is a trustee.

On April 21, 2010, we also entered into a Registration Rights Agreement, with the purchasers in the 2010 Warrant Financing pursuant to which we agreed to prepare and file a registration statement with the SEC, which was declared effective by the SEC on or prior to May 31,June 4, 2010 for purposes of registering the resale of the shares underlying the warrants and any shares of common stock issued as a dividend or other distribution with respect to the such shares. We agreed to use our reasonable best efforts to cause this registration statement to be declared effective by the SEC within 90 days after the closing of the Transactions (105 days in the event the registration statement is reviewed by the SEC). We also agreed, among other things, to indemnify the selling holders under the registration statement from certain liabilities and to pay all fees and expenses (excluding underwriting discounts and selling commissions and all legal fees of any selling holder) incident to our obligations under the Registration Rights Agreement.

March 2008 Financing.On March 25, 2008, we closed the sale of shares of our common stock and warrants to purchase shares of our common stock to certain accredited investors, including the related parties below, which we refer to collectively as the March 2008 Related Parties, in a private placement, which we refer to as the March 2008 Financing, generating gross proceeds of approximately $25.3 million, after collection of the note receivable issued by Paperboy Ventures LLC related to this financing of $6.0 million. The securities were sold at a purchase price of $2.77 per share of common stock and $0.125 per warrant. The warrants have a three-year term and an exercise price of $2.77 per share.

15


In connection with the March 2008 Financing, the March 2008 Related Parties purchased the shares of common stock and warrants at the aggregate purchase prices set forth below:

Name of March 2008 Related Party

  Number of
Shares of
Common
Stock
  Number of
Shares
Underlying
Warrants
  Aggregate
Purchase
Price

Longitude Ventures Partners, L.P.(1)

  3,530,450  1,765,225  $10,000,000

Paperboy Ventures, LLC(2)

  2,118,270  1,059,135  $6,000,000

Sutter Hill Ventures, L.P. and affiliated entities(3)

  1,581,311  790,653  $4,479,063

Alta Biopharma Partners II, L.P. and affiliated entity(4)

  1,059,135  529,567  $3,000,000

Joseph C. Cook, Jr.(5)

  176,522  88,261  $500,000

David L. Mahoney(6)

  70,609  35,304  $200,000

James N. Wilson(7)

  35,304  17,652  $100,000

(1)

Patrick Enright, a member of our Board is a managing member of the Longitude Capital Partners, the general partner of Longitude Venture Partners, L.P.

(2)

Allen Andersson, a member of our Board at the time of the March 2008 Financing, is the chairman and sole voting member of Paperboy Ventures, LLC. The majority of the securities purchased in this transaction by Paperboy Ventures, LLC have been sold on the open market as of April 21, 2010.

(3)

Consists of (a) 693,118 shares of common stock and a warrant to purchase 346,559 shares of common stock purchased by Sutter Hill Ventures, L.P., (b) 335,393 shares of common stock and a warrant to purchase 167,696 shares of common stock purchased by Mr. Baker, as Trustee of The Baker Revocable Trust., (c) 105,914 shares of common stock and a warrant to purchase 52,957 shares of common stock purchased by Saunders Holdings, L.P., of which Mr. Baker is a general partner, (d) 147,743 shares of common stock and a warrant to purchase 73,871 shares of common stock purchased by Tench Coxe and Simone Otus Coxe, Co-Trustees of The Coxe Revocable Trust under agreement dated 4/23/98, (e) 115,691 shares of common stock and a warrant to purchase 57,845 shares of common stock purchased by Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO William H. Younger, Jr., (f) 109,036 shares of common stock and a warrant to purchase 54,518 shares of common stock purchased by Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO David L. Anderson, (g) 17,940 shares of common stock and a warrant to purchase 8,970 shares of common stock purchased by Gregory P. and Sarah J.D. Sands Trust under agreement dated 2/24/99, (h) 17,574 shares of common stock and a warrant to purchase 8,787 shares of common stock purchased by Tallac Partners, L.P., of which James C. Gaither is a general partner, (i) 17,233 shares of common stock and a warrant to purchase 8,616 shares of common stock purchased by The White Family Trust under agreement dated 4/3/97, (j) 15,518 shares of common stock and a warrant to purchase 7,759 shares of common stock purchased by Jeffrey W. and Christina R. Bird Trust under agreement dated 10/31/00 and (k) 6,151 shares of common stock and a warrant to purchase 3,075 shares of common stock purchased by Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO David E. Sweet (Rollover). G. Leonard Baker, Jr., a member of our Board, is a partner and managing director of Sutter Hill Ventures, L.P. and may be deemed to have beneficial ownership of the shares discussed in parts (a) through (c) of this footnote. See the discussion in “Security Ownership of Certain Beneficial Owners and Management” for a discussion regarding the beneficial ownership of the Sutter Hill Principals.

(4)

Consists of (a) 1,045,921 shares of common stock and a warrant to purchase 522,960 shares of common stock purchased by Alta Biopharma Partners II, L.P. and (b) 13,214 shares of common stock and a warrant to purchase 6,607 shares of common stock purchased by Alta Embarcadero Biopharma Partners II, LLC. Alix Marduel, M.D, who was a member of our Board at the time of the March 2008 Financing, was a managing director of Alta Biopharma Partners II, L.P. and a manager of Alta Embarcadero Biopharma Partners II, LLC at the time of the March 2008 Financing.

(5)

Consists of shares and warrants purchased by The 2008 Cook Grantor Retained Annuity Trust, referred to as the Cook GRAT, of which Joseph C. Cook, Jr., a member of our Board, is the trustee. The holdings of the Cook GRAT were transferred to Joseph C. Cook, Jr., and Judith Cook as tenants in common in April 2009.

(6)

Consists of shares and warrants purchased by The David L. Mahoney and Winnifred C. Ellis 1998 Family Trust, of which David L. Mahoney, a member of our Board, is a trustee.

(7)

Consists of shares and warrants purchased by the James N. & Pamela Wilson Trust, or the Wilson Trust, of which James Wilson, a member of our Board, is the trustee. Immediately following issuance, the warrant purchased in this transaction by the Wilson Trust was assigned to the James and Pamela Wilson Family Partners.

Issuance of Shares of Common Stock in Settlement of Liquidated Damages.    In addition, on November 11, 2008, we entered into an Amendment to Registration Rights Agreement, or Amendment, which amended the Registration Rights Agreement, dated as of March 14, 2008, or Original Agreement, by and among us and the

16


investors in the March 2008 Financing described above, which we refer to as the Holders. Pursuant to the Amendment, on November 11, 2008, we agreed to issue an aggregate of 883,155 shares of our common stock, valued at $1.45 per share (the closing market price of our common stock on the NASDAQ Capital Market on November 11, 2008) as full satisfaction for approximately $1.3 million in liquidated damages owed to the Holders under the Original Agreement. In settlement of the liquidated damages discussed above, the March 2008 Related Parties received shares of common stock as liquidated damages in the amounts and at the values set forth below:

Name of March 2008 Related Party

  Number of
Liquidated
Damages
Shares
  Value

Longitude Ventures Partners, L.P.(1)

  349,425  $506,667

Paperboy Ventures, LLC(2)

  209,655  $304,000

Sutter Hill Ventures, L.P. and affiliated entities(3)

  156,503  $226,939

Alta Biopharma Partners II, L.P. and affiliated entity(4)

  104,826  $152,000

Joseph C. Cook, Jr.(5)

  17,471  $25,333

David L. Mahoney(6)

  6,988  $10,133

James N. Wilson(7)

  3,494  $5,067

(1)

Patrick Enright, a member of our Board is a managing member of Longitude Capital Partners, the general partner of Longitude Venture Partners, L.P.

(2)

Allen Andersson, a member of our Board at the time of the liquidated damages issuance, is the chairman and sole voting member of Paperboy Ventures, LLC. The majority of the securities acquired in this transaction by Paperboy Ventures, LLC have been sold on the open market as of April 21, 2010.

(3)

(a) Consists of 68,601 shares of common stock issued to Sutter Hill Ventures, L.P., (b) 33,195 shares of common stock issued to The Baker Revocable Trust., (c) 10,482 shares of common stock issued to Saunders Holdings, L.P., (d) 14,622 shares of common stock issued to Tench Coxe and Simone Otus Coxe, Co-Trustees of The Coxe Revocable Trust under agreement dated 4/23/98, (e) 11,450 shares of common stock issued to Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO William H. Younger, Jr., (f) 10,791 shares of common stock issued to Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO David L. Anderson, (g) 1,775 shares of common stock issued to Gregory P. and Sarah J.D. Sands Trust under agreement dated 2/24/99, (h) 1,739 shares of common stock issued to Tallac Partners, L.P., of which James C. Gaither is a general partner, (i) 1,705 shares of common stock issued to The White Family Trust under agreement dated 4/3/97, (j) 1,535 shares of common stock issued to Jeffrey W. and Christina R. Bird Trust under agreement dated 10/31/00 and (k) 608 shares of common stock issued to Wells Fargo Bank, N.A. FBO SHV Profit Sharing Plan FBO David E. Sweet (Rollover). G. Leonard Baker, Jr., a member of our Board, is a partner and managing director of Sutter Hill Ventures, L.P. and may be deemed to have beneficial ownership of the shares discussed in parts (a) through (c) of this footnote. See the discussion in “Security Ownership of Certain Beneficial Owners and Management” for a discussion regarding the beneficial ownership of the Sutter Hill Principals.

(4)

Consists of (a) 103,519 shares of common stock issued to Alta Biopharma Partners II, L.P. and (b) 1,307 shares of common stock issued to Alta Embarcadero Biopharma Partners II, LLC. Edward E. Penhoet, Ph.D., who was a member of our Board at the time of the issuance of the liquidated damage shares in November 2008, is a director and a limited partner of Alta Biopharma Partners II, L.P. and a member of Alta Embarcadero Biopharma Partners II, LLC.

(5)

Consists of shares issued to The 2008 Cook Grantor Retained Annuity Trust, of which Joseph C. Cook, Jr., a member of our Board, is the trustee. The holdings of the Cook GRAT were transferred to Joseph C. Cook, Jr., and Judith Cook as tenants in common in April 2009.

(6)

Consists of shares issued to The David L. Mahoney and Winnifred C. Ellis 1998 Family Trust, of which David L. Mahoney, a member of our Board, is a trustee.

(7)

Consists of shares issued to the James N. & Pamela Wilson Trust, of which James Wilson, a member of our Board, is the trustee.

Dr. Roe Promissory Note.    We entered into an agreement with Robert L. Roe, M.D., our President, dated October 18, 2001, pursuant to which Dr. Roe received an option to purchase 250,000 shares of our common stock

with an exercise price of $0.75 per share and a loan in the amount of $187,250, subject to interest rate of 6.5% and evidenced by a full-recourse promissory note to us to finance the exercise of the option. Through December 2009,April 10, 2011, Dr. Roe had repaid $99,705$170,263 of the principal of the loan plus accrued interest, leaving a total remaining principal balance of $87,545$16,987 plus accrued interest in the amount of $52,340$58 for a total combined balance of $139,885.$17,045.

17


Severance and Change in Control Agreements.    DuringIn September 2008, we entered into Amended and Restated Severance and Change in Control Agreements with each of our executive officers:officers at that time: Joseph K. Belanoff, M.D., Chief Executive Officer; Robert L. Roe, M.D., President; Caroline M. Loewy, Chief Financial Officer, and AnneM. LeDoux, Chief Accounting Officer. The terms of the agreements are identical. Subsequently, as additional executive officers have joined our company (Caroline M. Loewy, Chief Financial Officer, in November 2008 and Steven Lo, Vice President for Commercial Operations, in September 2010) we entered into a Severance and Change in Control Agreement with each of them, the provisions of which are identical to the severance and change in control agreements with our other executive officers. The agreements provide that, if employment is terminated without cause or for good reason regardless of whether it is in connection with a change in control, the executive will be eligible for 12 months of his or her then current base salary and continued health insurance coverage for this same period. In addition, the agreements provide for the full vesting of all outstanding equity awards in the event the executive’s employment is terminated without cause or for good reason within 18 months following a change in control.

During 2008, we also entered into an Amended and Restated Severance and Change in Control Agreement with James N. Wilson, Chairman of the Board of Directors.our Board. The agreement with Mr. Wilson provides that if his employment or service on theour Board terminates involuntarily without cause or good reason within eighteen18 months of a change in control all of his outstanding equity awards shall become fully vested.

Abbrah Engagement.    On May 23, 2008 the Board of Directors approved the engagement of Abbrah Publishing LLC, or Abbrah, a firm in which the son of James N. Wilson, our Chairman of the Board, is a principal, to assist us in the preparation and placement of materials to facilitate the recruitment of patients in its Cushing’s Syndrome trial, based on, among other things, the special qualifications of Abbrah and its willingness to accept performance-based compensation of its services. Compensation to Abbrah is based the number of patients actually enrolled in the study based on their materials. An initial payment was due upon patient enrollment, with an additional amount due if the patient completes the study. During the term of the agreement, the Company recorded expense of $42,000 as compensation to Abbrah in connection with these services assuming patient completion in the study. No additional amounts are expected to be incurred under this agreement.

Director Indemnification Agreements.We have entered into indemnification agreements with our directors and executive officers. Such agreements require us, among other things, to indemnify its officers and directors, other than for liabilities arising from willful misconduct of a culpable nature, and to advance their expenses incurred as a result of any proceedings against them as to which they could be indemnified.

See “Director Compensation” for a discussion of our director compensation policy.

SECTION 16(A) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

Under Section 16(a) of the Exchange Act and SEC rules, our directors, executive officers and beneficial owners of more than 10% of any class of equity security are required to file periodic reports of their ownership, and changes in that ownership, with the SEC. Based solely on our review of copies of these reports and representations of such reporting persons, we believe that during 2009,2010, such SEC filing requirements were satisfied.satisfied, with the exception of one Form 4 for each of Joseph C. Cook, Jr., James Harper and David Mahoney disclosing one transaction each that were inadvertently filed late.

EXECUTIVE COMPENSATION

Compensation Discussion and Analysis

The Compensation Committee of our Board is delegated the primary responsibility for our executive compensation program, which is intended to provide compensation packages for our named executive officers that are appropriately competitive within our industry, provide rewards for significant corporate performance and are appropriate for our stage of development. Compensation packages are designed to encourage a balanced focus on both short- and long-term goals. Direct compensation consists of a base salary, periodic cash bonuses for the achievement of significant corporate milestones and long-term equity incentive awards.

Executive Summary

During 2010, we had significant development, operational and financing accomplishments. Following is a summary of our principal activities and accomplishments over the course of the year.

·

We announced in December 2010 and January 2011, respectively, that our Phase 3 study of CORLUX for the treatment of Cushing’s Syndrome had met both of its primary endpoints and its key secondary endpoints with statistical significance.

·

We enrolled 88% of the patients who completed the six-month Phase 3 study of CORLUX for Cushing’s Syndrome in the long-term extension study of the treatment. We now have patients treated with CORLUX through our Phase 3 and extension studies for over two years.

·

We initiated a Phase 1b/2a multi-dose safety and proof of concept study in December 2010 with CORT 108297, the lead product candidate from our research efforts focusing on the identification and development of new, proprietary, selective glucocorticoid receptor II (GR-II) antagonists. The study is evaluating the compound in models of antipsychotic induced weight gain and changes in biomarkers induced by prednisone, a steroid.

·

We raised approximately $24.3 million in gross proceeds in a combination of public and private financing transactions.

Further, we continued to make progress on:

·

preparing for the submission to the U.S. Food and Drug Administration, or FDA, of our New Drug Application, or NDA, for CORLUX in Cushing’s Syndrome, which submission occurred on April 15, 2011;

·

planning for the potential commercialization of CORLUX in the United States;

·

enrolling patients in our double-blind placebo controlled Phase 3 trial of CORLUX in patients with psychotic depression;

·

advancing our second selective GR-II antagonist, CORT 113083, towards the submission to the FDA of an Investigational New Drug, or IND, application in 2011, and

·

identifying additional compounds from among our three proprietary series of selective GR-II antagonists to advance toward an IND submission.

Executive Compensation 2010 Program Overview

Based on our compensation philosophy, pay program structure and company and individual performance, our Compensation Committee took the following actions with respect to the compensation for our named executive officers for 2010:

Base Salary.    For our named executive officers who were employed for the entire year (Dr. Belanoff, our Chief Executive Officer, Dr. Roe, our President, Caroline M. Loewy, our Chief Financial Officer, and Anne LeDoux, our Vice President and Controller (Chief Accounting Officer), base salary for 2010 reflected an increase of 3%, as compared to the base salary of 2009, consistent with the increase provided to all company employees. The initial base salary (and option grant award) for Steven Lo, our Vice President of Commercial Operations, who joined the company in September 2010, was based on internal and external comparisons, the depth of his prior experience in commercializing new products at former companies and the level of cash and equity compensation that the Chief Executive Officer and members of our Compensation Committee and Board believed was appropriate for this position.

Bonus for 2010 Performance.    In view of the strong development and corporate performance accomplished by our company during 2010, our Compensation Committee and Board decided to award discretionary bonuses

to our named executive officers and other employees. Bonuses awarded to our named executive officers for 2010 performance ranged from approximately 30% to 100% of base pay received during that year. These awards reflect our achievement of significant corporate milestones for 2010, as well as the individual contribution to this performance by each named executive officer. The magnitude of the bonus awards for 2010 were based on 1) the significance of our development, operational and financing accomplishments during the year as discussed above, 2) the fact that accomplishments related to clinical trials and research activities often require more than a one year time span to complete and 3) the fact that we did not award bonuses to our named executive officers in 2009.

Equity Awards.    The Compensation Committee and Board chose not to award any new option grants during 2010 to our named executive officers, other than the award to Steven Lo upon his joining our company in September 2010. As discussed above, the size of the initial stock award for Steven Lo was based on the level of compensation that the Chief Executive Officer and members of our Compensation Committee and Board believed was appropriate for this position and the depth of Mr. Lo’s prior experience.

Compensation Principles and Objectives

For Joseph K. Belanoff, M.D., our Chief Executive Officer, Robert L. Roe, M.D., our President, Caroline M. Loewy, our Chief Financial Officer, Steven Lo, our Vice President of Commercial Operations, and Anne LeDoux, our Vice President and Controller (Chief Accounting Officer), our named executive officers, or NEOs, compensation is intended to be performance-based, with the exception of such NEOs’named executive officer’s base salary. The Compensation Committee believes that compensation paid to NEOsour named executive officers should be closely aligned with our performance on both a short-term and long-term basis, linked to specific, measurable results intended to create value for stockholders, and that such compensation should assist us in attracting and retaining key executives critical to our long-term success.

18


In establishing compensation for executive officers, the following are the Compensation Committee’s objectives:

 

 · 

Attract and retain individuals of superior managerial talent;

·

Ensure senior officer compensation is aligned with our corporate strategies, business objectives and the long-term interests of our stockholders;

·

Increase the incentive to achieve key strategic and financial performance measures by linking incentive award opportunities to the achievement of performance goals in these areas; and

·

Alignalign officer and stockholder interests as well as promote retention of key people, by providing a portion of total compensation opportunities for senior management in the form of direct ownershipequity awards and bonuses tied to company and individual performance.

·

ensure executive officer compensation is competitive within the marketplace in which we compete for executive talent by relying on the Compensation Committee’s judgment, expertise and personal experience with other similar companies, recognizing that because of the company’s business model and stage of development, there may be few directly comparable companies; and

·

recognize that best compensation practices for a young company with relatively few employees may be substantially different than for a larger, more mature company and that we should make full use of our company through stock options.greater latitude and breadth of compensation opportunities.

Our overall compensation program is structured to attract, motivate and retain highly qualified executive officers by paying them competitively, consistent with our success and their contribution to that success. WeGiven the long product development cycles in our business, we believe compensation should be structured to ensure that a portion of compensation opportunity will be directly related to our stock performance and other factors that directly and indirectly influence long-term stockholder value. Accordingly, we set goals designed to link each NEO’snamed executive officer’s compensation to our corporate performance, such as the attainment of clinicaldevelopment and operational goals and meeting agreed upon financial targets.

We provide a base salary to our executive officers. Additionally, consistent with our performance-based philosophy, we reserve the largest potential compensation awards for performance- and incentive-based programs for our senior executive management team, comprised of the Chief Executive Officer, President, Chief Financial Officer, Vice President of Commercial Operations and Chief Accounting Officer. Such programs

include stock options grants, designed to provide compensation opportunities if milestones are attained that increase our value, such as positive results in clinical trials, are attained.trials. Incentive-based programs provide compensation in the form of both cash and equity, to reward for both short-term and long-term performance. The Compensation Committee allocates total compensation between cash and equity compensation based on the Compensation Committee members’ knowledge of compensation practices in the biotechnology and specialty pharmaceutical industries. The balance between equity and cash compensation among members of the senior executive management team, all fourfive of whom are NEOs,named executive officers, is evaluated annually to align the interests of management with stockholders through both short and long term incentives.

The Chairman of the Board and the members of the Compensation Committee are seasoned executives of, consultants to or venture capitalists with investments in the biotechnology and specialty pharmaceutical industry. Collectively they have served as board and compensation committee members of many public and privately held companies including Amylin Pharmaceuticals, Inc., Ironwood Pharmaceuticals, Inc., NuGen Technologies, Inc., Neurex Corporation, Praecis Pharmaceuticals, Inc., Syntex Corporation, Tercica, Inc. and Zymogenetics Inc. As a result of this extensive involvement in the compensation of executives in these and other companies, the Chairman of the Board and the members of the Compensation Committee collectively have developed a clear understanding and knowledge of the compensation structures that are necessary to attract, motivate and retain management talent.

Determination of Compensation

The Compensation Committee is providedcharged with the primary authority to determine and recommend the compensation awards available to our executive officers for approval by the Board of Directors.Board. Based on the Compensation Committee members’ collective understanding of compensation practices in similar companies in the biotechnology and specialty pharmaceutical industry, our executive compensation package consists of the following elements, in addition to the employee benefit plans in which all employees may participate:

 

 · 

Base salary: compensation for ongoing performance throughout the year.

 

 · 

Periodic performance-based cash compensation: awards to recognize and reward achievement of performance goals.

 

19


 · 

Long-term performance-based equity incentive program: equity compensation to provide an incentive to the NEOsour named executive officers to manage us from the perspective of an owner with an equity stockstake in the business.

 

 · 

Severance and change in control benefits: remuneration paid to executives in the event of a change in control or involuntary employment termination.

To aid the Compensation Committee in making its determination, our Chief Executive Officer provides recommendations annually to the Compensation Committee regarding the compensation of all other executive officers. Each NEO in turn, participates in an annual performance review with our Chief Executive Officer to provide input about theirofficers based on the overall corporate achievements during the period being assessed and his knowledge of the individual contributions to our success forby each of the period being assessed.named executive officers. The overall performance of our senior executive management team is reviewed annually by the Compensation Committee.

We set base salary structures and any grants of stock options based on the Compensation Committee members’ collective understanding of compensation practices in the biotechnology and specialty pharmaceutical industry and such members’ experiences as seasoned executives, consultants, board and compensation committee members, or investors in similar biotechnology and specialty pharmaceutical industry companies.

Tax Considerations

A goal of the Compensation Committee is to comply with the requirements of Internal Revenue Code Section 162(m) of the Internal Revenue Code of 1986, as amended, which limits the tax deductibility by us of

annual compensation in excess of $1,000,000 paid to our Chief Executive Officer and any of our three other most highly compensated executive officers, other than our Chief Financial Officer. However, performance-based compensation that has been approved by our stockholders is excluded from the $1,000,000 limit if, among other requirements, the compensation is payable only upon the attainment of pre-established, objective performance goals and the committee of our Board of Directors that establishes such goals consist only of non-employee directors.

While the tax impact of any compensation arrangement is one factor to be considered, such impact is evaluated in light of the Compensation Committee’s overall compensation philosophy and objectives. The Compensation Committee will consider ways to maximize the deductibility of executive compensation, while retaining the discretion it deems necessary to compensate officers in a manner commensurate with performance and the competitive environment for executive talent. From time to time, the Compensation Committee may award compensation to our executive officers which isthat may not be fully deductible if it determines that such award is consistent with its philosophy and is in our and our stockholders’ best interests.

Certain option grants made under our equity plans are intended to be structured so that any compensation deemed paid upon the exercise of those options is intended to qualify as performance-based compensation that is not subject to the $1,000,000 limitation.

Elements of Executive Compensation

BASE COMPENSATIONBase Compensation

We pay base salaries to provide fixed compensation based on the Compensation Committee’s assessment of competitive market practices. Due to the Compensation Committee’s collective experience with similar companies in the biotechnology and specialty pharmaceutical industry, the Compensation Committee has intricateintimate knowledge and understanding of what the industry demands in order to motivate and retain our executive officers. We provide each NEOnamed executive officer with a base salary that was established by extensive negotiations with each NEOnamed executive officer when such individual first joined us as an employee or was promoted to the position of executive officer. Base salaries have not changed in 20092010 as compared to 20082009 other than for annual merit adjustments of

20


3% per year that were approved by the Compensation Committee and applied equally to all employees. While base salaries are not considered by the Internal Revenue Service to constitute performance-based compensation, each year the Compensation Committee reviews the CEO’s base salary to determine if a change is appropriate based on Company performance, such as our progress on research and development programs. Similarly, the CEO reviews the base salary of the other NEOsnamed executive officers and has the ability to propose a change in base salary based on performance to the Compensation Committee. Other than the annual merit increases that the Compensation Committee has approved, no formulaic base salary increases are provided to the NEOs.named executive officers.

PERFORMANCE-BASED COMPENSATIONPerformance-Based Compensation

Performance Goals and Periodic Performance-Based Cash CompensationCompensation.

We structure our compensation programs to reward executive officers based on our performance. This allows executive officers to receive bonus compensation in the event certain specified corporate performance measures are achieved. To date, we have not instituted an annual performance-based cash compensation or annual performance-based equity compensation program because the Compensation Committee believes that the compensation objective to ensure that executive officers’ compensation is aligned with our corporate strategies, business objectives and the long-term interests of our stockholders is achieved when milestone successes are met, such as meeting the predetermined endpoints in our clinical trials. The achievement of these milestones does not necessarily correspond with annual performance periods.

Performance-based cash compensation has been awarded in some past years primarily to recognize the attainmentaccomplishment of certain accomplishments of value enhancing milestones such as successful financing transactions, initiation of clinical trials and positive results in clinical trials. The Compensation Committee believes that performance-based compensation should be based on achievement of certainthese types of milestone successes, such assuccesses.

On December 21, 2010, our Board approved cash bonus payments for the attainment2010 fiscal year to our named executive officers and all other employees. These bonus awards were made in connection with important achievements during 2010, including the completion of predetermined end-points in our clinical trials, successful financing transactions andfor aggregate gross proceeds of approximately $24.3 million, the reporting of positive results from our Phase 3 study of CORLUX for the treatment of Cushing’s Syndrome, the commencement of certaincommercialization planning activities for that program, and progress in the development of new chemical entities, including clinical trials. No bonusesdevelopment of CORT 108297 and the initiation of preliminary activities toward filing an IND for CORT 113083. For a more comprehensive discussion of our corporate accomplishments during 2010, see the section captioned “Executive Summary” under this Compensation Discussion and Analysis that appears on page 15.

The bonus amounts paid to our named executive officers for 2010 performance were awardedas follows:

Name

 

Title

 Bonus
Amount
  Percentage of
2010 Base Pay
 

Joseph K. Belanoff, M.D.

 Chief Executive Officer $454,000    100

Robert L. Roe, M.D.

 President and Secretary  315,000    75

Caroline M. Loewy

 Chief Financial Officer  93,000    30

Steven Lo(1)

 Vice President of Commercial Operations  25,000    30

Anne M. LeDoux

 Vice President, Controller and Chief Accounting Officer  66,000    30

(1)

Steven Lo received a prorata bonus reflecting the fact that he was only with us for part of the year.

For each named executive officer, the bonus amount was based on his or her relative individual contribution to our success and the NEOs for 2009.breadth of his or her sphere of responsibility, which are enumerated below.

Name

Title

Individual Contribution

Joseph K. Belanoff, M.D.

Chief Executive OfficerOverall leadership and direction of the company’s activities in a productive and successful year, including leading financings and directing research programs for selective GR-II antagonists

Robert L. Roe, M.D.

President and SecretaryLeadership of all drug evaluation and development activities relating to the successful clinical trial for CORLUX for Cushing’s Syndrome and the preparations for its NDA submission; the initiation of clinical development of CORT 108297 and of pre-clinical work on CORT 113083

Caroline M. Loewy

Chief Financial OfficerOrganization of financing activities resulting in $24.3 million in gross proceeds and direction of investor and public relations

Steven Lo

Vice President of Commercial OperationsOrganization and leadership of our commercialization activities, including the development of our Risk Evaluation and Mitigation Strategy

Anne M. LeDoux

Vice President, Controller and Chief Accounting OfficerManagement of financial operations, SEC regulatory filings for financing and periodic reporting, resulting in successful initial year of auditor attestation under Sarbanes-Oxley Section 404.

Long-Term Performance-Based Equity Incentive ProgramProgram.

Our executive officers, along with all of our employees, are eligible to participate in our awarding of stock options under our 2004 Equity Incentive Plan. As discussed above, we believe, with our performance-based approach to compensation, that equity ownership in the Companyour company is important to tie the ultimate level of an executive officer’s compensation to the performance of our stock and stockholder gains while creating an incentive for sustained growth. We have, thus far, only used stock options as the long-term performance-based equity incentive vehicle because the Compensation Committee believes that stock options maximize executive officers’ incentive to increase our stock price and maximize stockholder value (i.e. there is no financial gain to an executive officer unless our stock price appreciates).

Equity compensation in the form of incentive or non-qualified stock options is awarded by the Compensation Committee from time to time. The size and the timing of each grant is based on a number of factors, including the executive officer’s salary, such executive officer’s contributions to the achievement of our financial and strategic objectives, the value of the stock option at the time of grant, the possible value of the option if we achieve our objectives and industry practices and norms from the collective knowledge of the Compensation Committee as seasoned executives of, consultants to, board and compensation members of, and venture capitalists with investments in similar companies in the industry. The relative weight given to each of these factors varies among individuals at the Compensation Committee’s discretion. There is no set formula for the granting of stock options to individual executives and employees. Grants also may be made following a significant change in job responsibility or in recognition of a significant achievement.

Stock options granted to NEOsour named executive officers under the various stockequity incentive plans generally have a four or five-yearmulti-year vesting schedule in order to provide an incentive for continued employmentemployment. These vesting schedules are generally either four or five years depending on the date of the initial option grant. In addition, a portion of the stock option awards granted to Dr. Belanoff and Dr. Roe in 2009 are performance-based grants that vest, in their entirety upon the approval of the NDA for the Company’s first product by the FDA (see footnote 2 to the Summary Compensation table presented below). Stock option awards generally expire ten years from the date

21


of the grant. This provides a reasonable time frame in which to provide the executive officer with the possibility of price appreciation of our shares. The exercise price of options granted under the stock plans is 100% of the fair market value of the underlying stock on the date of grant.

During 2009,2010, the Compensation Committee and Board of Directors approved the award of a stock option grantsgrant of 400,000 shares to Joseph K. Belanoff, our CEO, Robert L. Roe, our President, and Anne M. LeDoux,Steven Lo, upon his joining the company as our Vice President Controller and Chief Accounting Officer. A portion of the vesting of the awards to Dr. Belanoff and Dr. Roe in the amounts of 500,000 shares and 200,000 shares, respectively, is subject to a performance-based condition under which these options will vest in their entirety upon the approval of the NDA for our Company’s first product by the FDA. The remainder of theCommercial Operations. This option awards in the amounts of 500,000 shares, 200,000 shares and 125,000 shares granted respectively to Dr. Belanoff, Dr. Roe and Mrs. LeDoux vest monthly on a pro-rata basisaward vests over a four-yearfour year period, fromwith 25% vesting on the first annual anniversary of Mr. Lo’s date of grant.employment and the remainder vesting at the rate of 2.0834% on each monthly anniversary thereafter until fully vested.

SEVERANCE AND CHANGE IN CONTROL ARRANGEMENTSSeverance and Change in Control Arrangements

We entered into Severance and Change in Control Agreements with each of our named executive officers to encourage continued attention and dedication to duties without distraction arising from the possibility of a change in control of our company and provide the business with a smooth transition in the event of a change in control. The terms of the agreements are identical. For a detailed description of the Severance and Change in Control Agreements, see “Potential Payments Upon Termination or Change in Control – Severance and Change in Control Agreements” below.

These severance and change in control arrangements are designed to retain these executives in these key positions as we compete for talented executives in the marketplace where such protections are commonly offered. These arrangements provide benefits to encourage the executives to continue to provide necessary or desirable service to us during a change in control and to ease the transition of the executives due to an unexpected employment termination by us due to changes in our employment needs.

OTHER ELEMENTS OF COMPENSATION AND PERQUISITESOther Elements of Compensation and Perquisites

401(k) Plan.    We have a Section 401(k) Savings/Retirement Plan, or 401(k) Plan, to cover our eligible employees and any designated affiliate. The 401(k) Plan permits our eligible employees to defer up to 100% of their annual compensation, subject to certain limitations imposed by the Internal Revenue Code. The employees’ elective deferrals are immediately vested and non-forfeitable upon contribution to the 401(k) Plan. We currently make no matching contributions to the 401(k) Plan. Our employees are eligible to participate in the 401(k) Plan, as well as the insurance programs discussed below, on the first day of the month coinciding with or immediately following the first day of employment.

Medical Insurance.    We, at our sole cost, provide to each eligible employee (including each NEO)named executive officer), and his or her spouse and children such health, dental and optical insurance as we, in our sole discretion, may from time to time make available to our other employees of the same level of employment.employees. Such insurance programs are part of an overall broad-based total compensation program designed to facilitate our ability to attract and retain employees as we compete for talented individuals in the marketplace where such benefits are commonly offered.

Life and Disability Insurance.    We, at our sole cost, provide each eligible employee (including each NEO)named executive officer) such disability and/or life insurance as we, in our sole discretion, may from time to time make available to our other employees of the same level of employment.employees. Such insurance programs are part of an overall broad-based total compensation program designed to facilitate our ability to attract and retain employees as we compete for talented individuals in the marketplace where such benefits are commonly offered.

22


POLICIES WITH RESPECT TO EQUITY COMPENSATION AWARDSPolicies with Respect to Equity Compensation Awards

We grant all stock option awards based on the fair market value as of the date of grant. We do not have a policy of granting stock option awards at other than the fair market value. The exercise price for each stock option grants is determined by looking at the fair market value ofbased on the last quoted price per share on the NasdaqNASDAQ Capital Market on the date of grant. We do not have a policy and do not intend to have a policy or practice to select option grant dates for executive officers in coordination with the release of material non-public information.

We also have an insider trading policy that prohibits our named executive officers and Board members from engaging in short-term or speculative transactions in our stock, including short sales.

SUMMARY COMPENSATION TABLESummary Compensation Table

The following table provides compensation information for the years ended December 31, 2010, 2009 2008 and 20072008 for each of our named executive officers.

 

Name and Principal

Position

  Year  Salary
($)
  Bonus
($)
  Option
Awards(1)

($)
 All Other
Compensation

($)
  Total
($)
  Year   Salary
($)
   Bonus
($)
   Option
Awards(1)

($)
 All Other
Compensation

($)
 Total
($)
 

Joseph K. Belanoff, M.D.,

  2009  $440,272     $909,350(2)    $1,349,622   2010    $453,480    $454,000     —      —     $907,480  

Chief Executive Officer

  2008  $427,448            $427,448   2009    $440,272     —      $909,350(2)   —     $1,349,622  
  2007  $411,008  $102,752  $1,130,000      $1,643,760   2008    $427,448     —       —      —     $427,448  

Caroline M. Loewy,

  2009  $300,000            $300,000   2010    $309,000    $93,000     —      —     $402,000  

Chief Financial Officer(3)

  2008  $25,000     $616,000      $641,000   2009    $300,000     —       —      —     $300,000  
   2008    $25,000     —      $616,000    —     $641,000  

Robert L. Roe, M.D.,

  2009  $405,745     $363,740(2)  $1,800  $771,285   2010    $417,918    $315,000     —     $900(5)  $733,818  

President

  2008  $393,927         $900  $394,827   2009    $405,745     —      $363,740(2)  $1,800(5)  $771,285  
  2007  $378,776  $95,294  $791,000   $2,400  $1,267,470   2008    $393,927     —       —     $900(5)  $394,827  

Steven Lo(4)

   2010    $88,636    $25,000    $1,084,000    —     $1,197,636  

Anne LeDoux,

  2009  $214,240     $113,588     $327,828   2010    $220,667    $66,000     —      —     $286,667  

Vice President and

Controller

  2008  $208,000  $20,800         $228,800   2009    $214,240     —      $113,588    —     $327,828  
2007  $191,777  $47,944  $141,250      $380,971

(Chief Accounting Officer)

              2008    $208,000    $20,800     —      —     $228,800  

 

(1)

Amounts shown do not reflect compensation actually received by the named executive officers or the actual value that may be recognized by the named executive officers with respect to these awards in the future. Instead, the amounts shown represent the grant date fair value of the awards as of the date of grant. The relevant assumptions used to calculate the value of the option awards are set forth underin Part IIIV – Item 815(1) – Financial Statements, Notes 1 – the Notes to Financial Statements, Note 9 Accounting Policies“Preferred Stock and EstimatesStockholders’ Equity – Stock-Based Compensation Related to Employees and Director Options” in our Annual Report on Form 10-K.

10-K for the year ended December 31, 2010.

 

(2)

The stock option grants awarded in 2009 to Joseph K. Belanoff, M.D. and Robert L. Roe, M.D., are each comprised of 2two parts. One-half of the shares of each award (500,000 shares for Dr. Belanoff and 200,000 shares for Dr. Roe) is a service-based award that vests pro rata over a four-year period at the rate of 2.0834% on the monthly anniversary of the date of grant, until fully vested. The remaining one-half of each award (500,000 shares for Dr. Belanoff and 200,000 shares for Dr. Roe) will vest in its entirety upon the occurrence of the approval of the NDA for ourthe Company’s first product by the FDA. The grant date fair value for these performance grants are $455,000 for the 500,000 share performance award to Dr. Belanoff and $182,000 for the 200,000 share performance award to Dr. Roe.

 

(3)

Caroline Loewy joined our companyus in November 2008 as Chief Financial Officer.

 

(4)Steven Lo joined us in September 2010 as Vice President of Commercial Operations.

23

(5)The amounts shown for Dr. Roe represent compensation in lieu of contributions to a Health Savings Account, which is a benefit provided to our other employees. Dr. Roe is not eligible to participate in a Health Savings Account by virtue of his having continued health coverage from a former employer.


GRANTS OF PLAN-BASED AWARDS DURING 2009Grants of Plan-Based Awards During 2010

The following table summarizes the grants of stock and option awards we made to the named executive officers in 2009.2010.

 

Name

  Grant
Date
  Estimated Future Payouts
Under Equity Incentive Plan Awards
  All Other
Option
Awards:
Number of
Securities
Underlying
Options(1)

(#)
  Exercise
or Base
Price of
Option
Awards
($/Sh)
  Grant
Date

Fair
Value
of Stock
and
Option
Awards(2)

($)
   Grant
Date
   Estimated Future Payouts
Under Equity Incentive Plan Awards
   All Other
Option
Awards:
Number of
Securities
Underlying
Options(1)

(#)
   Exercise
or Base
Price of
Option
Awards
($/Sh)
   Grant Date
Fair Value
of Stock and
Option
Awards(2)

($)
 
  Threshold
(#)
  Target
(#)
 Maximum
(#)
        Threshold
(#)
   Target
(#)
   Maximum
(#)
   

Joseph K. Belanoff, M.D.(4)

  3/26/09    500,000(3)    500,000(3)  $1.19  $909,350(3)                                    

Caroline M. Loewy(4)

                                                       

Robert L. Roe, M.D.(4)

  3/26/09    200,000(3)    200,000(3)  $1.19  $363,740(3)                                    

Anne LeDoux

  3/26/09         125,000(4)  $1.19  $113,588  

Steven Lo(3)

   9/24/10                    400,000    $3.51    $1,084,000  

Anne LeDoux(4)

                                   

 

(1)

The options were granted under our 2004 Equity Incentive Plan.

 

(2)

The value of the option award is based on the fair value as of the grant date of the award multiplied by the number of shares. Refer to Note 9 – “Preferred Stock and Stockholders’ Equity – Stock-Based Compensation Related to Employees and Director Options” included in Part IIIV – Item 815(1) – Financial Statements, – Note 1 – Accounting Policies and Estimates – Stock-Based CompensationNotes to Financial Statements, in our Annual Report on Form 10-K for the year ended December 31, 2010 for the relevant assumptions used to determine the valuation of our option awards.

 

(3)

The stock option grantsgrant awarded to Joseph K. Belanoff, M.D. and Robert L. Roe, M.D., are each comprised of 2 parts. One-half of the shares of each award (500,000 shares for Dr. Belanoff and 200,000 shares for Dr. Roe) is a service-based award thatMr. Lo vests pro rata over a four-yearfour year period with 25% vesting on the first annual anniversary of Mr. Lo’s date of employment and the remainder vesting at the rate of 2.0834% on theeach monthly anniversary of the date of grant,thereafter until fully vested. The remaining one-half of each award (500,000 shares for Dr. Belanoff and 200,000 shares for Dr. Roe) will vest in its entirety upon the occurrence of the approval of the NDA for our Company’s first product by the FDA. The grant date fair value for these performance grants are $455,000 for the 500,000 share performance award to Dr. Belanoff and $182,000 for the 200,000 share performance award to Dr. Roe.

 

(4)

The stockThere were no new option grants awardedduring 2010 to Dr. Belanoff, Ms. LeDoux is a service-based award that vests pro rata over a four-year period at the rate of 2.0834% on the monthly anniversary of the date of grant, until fully vested.Loewy, Dr. Roe or Ms. LeDoux.

24


OUTSTANDING EQUITY AWARDS AT FISCAL YEAR-ENDOutstanding Equity Awards At Fiscal Year-End

The following table summarizes unexercised options that have not vested and related information for each of our named executive officers as of December 31, 2009.2010.

 

  Option Awards  Option Awards 

Name

  Number
of
Securities
Underlying
Unexercised
Options

Exercisable
(#)
 Number
of
Securities
Underlying
Unexercised
Options

Unexercisable
(#)
 Equity
Incentive
Plan
Awards:
Number

of
Securities
Underlying
Unexercised
Unearned
Options

(#)
 Option
Exercise
Price

($)
  Option
Expiration
Date
  Grant Date   Number of
Securities
Underlying
Unexercised
Options

Exercisable
(#)
 Number of
Securities
Underlying
Unexercised
Options

Unexercisable
(#)
 Equity
Incentive
Plan
Awards:
Number of
Securities
Underlying
Unexercised
Unearned
Options

(#)
 Option
Exercise
Price

($)
   Option
Expiration
Date
 

Joseph K. Belanoff, M.D.

  666,688(3)  333,312(3)     $1.50  4/16/2017   

 

4/16/2007

3/26/2009

  

  

   

 

916,696

218,757

(2) 

(3) 

  

 

83,304

281,243

(2) 

(3) 

  

 


500,000

  

(3) 

 $

$

1.50

1.19

  

  

   

 

4/16/2017

3/26/2019

  

  

  93,753(4)  406,247(4)  500,000(4)  $1.19  3/26/2019

Caroline M. Loewy

  216,673(2)  583,327(2)     $1.02  11/28//2018   11/28/2008     416,680(1)   383,320(1)      $1.02     11/28//2018  

Robert L. Roe, M.D.

  10,000(1)        $0.10  10/1/2010   

 

 

 

 

11/23/2003

2/10/2005

3/2/2006

4/16/2007

3/26/2009

  

  

  

  

  

   

 

 

 

 

100,000

100,000

50,000

641,687

87,502

  

  

  

(2) 

(3) 

  

 

 

 

 


58,313

112,498

  

  

  

(2) 

(3) 

  

 

 

 

 


200,000

  

  

  

  

(3) 

 $

$

$

$

$

7.00

4.82

4.95

1.50

1.19

  

  

  

  

  

   

 

 

 

 

11/23/2013

2/10/2015

3/2/2016

4/16/2017

3/26/2019

  

  

  

  

  

  100,000(1)        $7.00  11/23/2013
  96,820(1)  3,180(1)     $4.82  2/10/2015
  46,876(2)  3,124(2)     $4.95  3/2/2016
  466,681(3)  233,319(3)     $1.50  4/16/2017
  37,501(4)  162,499(4)  200,000(4)  $1.19  3/26/2019

Steven Lo

   9/24/2010         400,000(1)      $3.51     9/24/2020  

Anne M. LeDoux

  17,500(1)        $12.00  4/16/2014   

 

 

 

 

4/16/2004

10/6/2004

9/23/2005

4/16/2007

3/26/2009

  

  

  

  

  

   

 

 

 

 

17,500

42,500

15,000

114,587

54,689

  

  

  

(2) 

(2) 

  

 

 

 

 


10,413

70,311

  

  

  

(2) 

(2) 

  

 

 

 

 


  

  

  

  

  

 $

$

$

$

$

12.00

7.73

5.70

1.50

1.19

  

  

  

  

  

   

 

 

 

 

4/16/2014

10/6/2014

9/23/2015

4/16/2017

3/26/2019

  

  

  

  

  

  42,500(1)        $7.73  10/6/2014
  12,769(1)  2,231(1)     $5.70  9/23/2015
  83,336(3)  41,664(1)     $1.50  4/16/2017
  23,438(3)  101,562(3)     $1.19  3/26/2019

 

(1)

The option vests at the rate of 20% at the first anniversary of the grant date and, thereafter, at the rate of 1.67% per month, until fully vested.

(2)

The option vests at the rate of 25% at the first anniversary of the grant date and, thereafter, at the rate of 2.0834% per month, until fully vested.

 

(3)(2)

The option vests at the rate of 2.0834% per month until fully vested.

 

(4)(3)

The stock option grants awarded to Joseph K. Belanoff, M.D. and Robert L. Roe, M.D., are each comprised of 2 parts. One-half of the shares of each award (500,000 shares for Dr. Belanoff and 200,000 shares for Dr. Roe) is a service-based award that vests prorata over a four-year period at the rate of 2.0834% on the monthly anniversary of the date of grant, until fully vested. The remaining one-half of each award (500,000 shares for Dr. Belanoff and 200,000 shares for Dr. Roe) will vest in its entirety upon the occurrence of the approval of the NDA for ourthe Company’s first product by the FDA.

OPTION EXERCISES AND STOCK VESTED

None of our named executive officers exercised stock options during 2009. To date, no stock awards have been granted to any of our named executive officers.

PENSION BENEFITSOption Exercises in 2010

The following table includes certain information with regard to options exercised by our named executive officers during 2010.

Name

  Option Exercises 
  Number of Shares  Acquired
(#)
   Value Realized on  Exercise
($)
 

Joseph K. Belanoff, M.D.

          

Caroline M. Loewy

          

Robert L. Roe, M.D.

   10,000    $28,400  

Steven Lo

          

Anne LeDoux

          

Pension Benefits

None of our named executive officers participate in or have account balances in qualified or non-qualified defined benefit plans sponsored by us.

25


NONQUALIFIED DEFERRED COMPENSATIONNonqualified Deferred Compensation

None of our named executives participate in or have account balances in non-qualified defined contribution plans or other deferred compensation plans maintained by us.

POTENTIAL PAYMENTS UPON TERMINATION OR CHANGE IN CONTROLPotential Payments Upon Termination or Change in Control

Severance and Change in Control Agreements

We have entered into Severance and Change in Control Agreements with each of our named executive officers: Joseph K. Belanoff, M.D., Chief Executive Officer; Robert L. Roe, M.D., President; Caroline M. Loewy, our Chief Financial Officer, Steven Lo, Vice President of Commercial Operations and Anne M. LeDoux, Vice President and Controller (Chief Accounting Officer). The terms of the agreements are identical. The agreements provide that, if employment is terminated without cause or for good reason regardless of whether it is in connection with a change in control, the executive will be eligible for 12 months of his or her then current base salary and continued health insurance coverage for such 12-month period. In addition, the agreements provide for the full vesting of all outstanding equity awards in the event the executive employment is terminated without cause or for good reason within 18 months following a change in control. The receipt of any severance will be subject to the executive signing and not revoking a separation agreement and release of claims in a form reasonably acceptable to us within 60 days following executive’s termination of employment. No severance will be paid or provided until the separation agreement and release of claims becomes effective.

The following table reflects compensation payable to each named executive officer under a change in control or various employment termination events. The amounts shown below assume that (i) a change in control of our company occurred on December 31, 2010 or (ii) eachsuch named executive officer terminated employment with our company was effective as of December 31, 2009,2010, and estimatesestimate the value to the named executive officer as a result of each triggering event.

 

Name

  

Benefit

  Termination
Without

Cause
  Involuntary
Termination
Other Than for
Death,
Disability or Cause
Within 18 Months
of Change in
Control
   

Benefit

  Termination
Without

Cause
   Involuntary
Termination
Other Than for
Death,
Disability or Cause
Within 18 Months
of Change in
Control
 

Joseph K. Belanoff, M.D.

  Base Salary  $440,272  $440,272    

Base Salary

Accelerated Vesting, of Stock Options(1)

Health Benefit

  $

 

$

453,480

—  

20,476

  

  

  

  $

$

$

453,480

2,282,516

20,476

  

(2) 

  

  Accelerated Vesting, of Stock Options(1)     $1,867,572(2) 
  Health Benefit  $22,892  $22,892  
                   
  

Total

  $463,164  $2,330,736            Total  $473,956    $2,756,472  
                   

Caroline M. Loewy

  Base Salary  $300,000  $300,000    

Base Salary

Accelerated Vesting, of Stock Options(1)

Health Benefit

  $

 

$

309,000

—  

5,776

  

  

  

  $

$

$

309,000

1,088,629

5,776

  

(2) 

  

  Accelerated Vesting, of Stock Options(1)     $1,026,656(2)           
  Health Benefit  $20,246  $20,246            Total  $314,776    $1,403,405  
                   
  

Total

  $320,246  $1,346,902  
         

Robert L. Roe, M.D.

  Base Salary  $405,745  $405,745    

Base Salary

Accelerated Vesting, of Stock Options(1)

Health Benefit

  $

 

$

417,918

—  

17,023

  

  

  

  $

$

$

417,918

971,989

17,023

  

(2) 

  

  Accelerated Vesting, of Stock Options(1)     $875,022(2)           
  Health Benefit  $17,846  $17,846            Total  $434,941    $1,406,930  
          

Steven Lo

  

Base Salary

Accelerated Vesting, of Stock Options(1)

Health Benefit

  $

 

$

300,000

—  

19,816

  

  

  

  $

$

$

300,000

140,000

19,816

  

(2) 

  

                   
  

Total

  $423,591  $1,298,613            Total  $319,816    $459,816  
                   

Anne M. LeDoux

  Base Salary  $214,240  $214,240    

Base Salary

Accelerated Vesting, of Stock Options(1)

Health Benefit

  $

 

$

220,667

—  

25,464

  

  

  

  $

$

$

220,667

212,305

25,464

  

(2) 

  

  Accelerated Vesting, of Stock Options(1)     $214,814(2)           
  Health Benefit  $28,009  $28,009            Total  $246,131    $458,436  
                   
  

Total

  $242,249  $457,063  
         

 

(1)

Assumes that the stock options were not assumed or substituted by the successor entity to our company or a parent or subsidiary of the successor entity.

 

26


(2)

For unvested options held by named executive officers as of December 31, 2009,2010, the value ascribed to the change in control acceleration features under the Severance and Change in Control Agreements is calculated as follows:

 

 a.For option grants to these individuals where the closing stock price for our company’s common stock on the NasdaqNASDAQ Capital Market as of December 31, 2009 had2010 exceeded the exercise price of the option grant, the value of the acceleration benefit on change in control has been calculated as the difference between these factors multiplied by the number of unvested shares in each of these option awards as of that date.

 

 b.There is no value ascribed to any unvested shares for any option grants to these individuals where the exercise price of the option grant equaled or exceeded the closing stock price for our company’s common stock on the NasdaqNASDAQ Capital Market as of December 31, 2009.2010.

EquityRisk Assessment of Compensation Plan InformationPrograms

Our Compensation Committee and Board have determined that our compensation policies, plans and practices are appropriately balanced and do not create risks that are reasonably likely to have a material adverse effect on the Company. To make this determination, they reviewed the compensation policies, plans and practices for our executive officers and employees assessing such features as design, payment methodology, relationship to the Company’s performance and length of performance period, and oversight and controls as compared to the compensation practices that they have seen in similar companies in our stage of development. During the review several risk mitigating factors inherent in the Company’s compensation practices were noted, including the Compensation Committee’s and management’s discretion in approving executive and employee compensation and establishing performance goals for short term and long term compensation plans, the balance between fixed and variable pay and the mix of short- and long-term incentives that encourage consistent performance over a sustained period , thus aligning the interests of our executive officers and employees with that of our stockholders.

EQUITY COMPENSATION PLAN INFORMATION

The following table provides information as of December 31, 20092010 with respect to the shares of our common stock that may be issued under all of our existing equity compensation plans, including the 2004 Equity Incentive Plan and the 2000 Stock Option Plan.

 

Plan Category

  (a)
Number of Securities
to Be Issued upon
Exercise of
Outstanding Options
  (b)
Weighted Average
Exercise Price of
Outstanding
Options
  (c)
Number of Securities
Remaining Available
for Future Issuance
under Equity
Compensation Plans
(Excluding Securities
Reflected in
Column(a))(2)
   (a)
Number of Securities
to Be Issued upon
Exercise of
Outstanding Options
   (b)
Weighted  Average
Exercise Price of
Outstanding
Options
   (c)
Number of  Securities

Remaining Available
for Future Issuance
under Equity
Compensation Plans
(Excluding Securities
Reflected in
Column(a))(2)
 

Equity compensation plans approved by stockholders

  7,346,636  $2.28  201,044(1)(2)    7,961,102    $2.40     1,948,907(1)(2) 

Equity compensation plans not approved by stockholders

            —       —       —    
                      

Total

  7,346,636  $2.28  201,044     7,961,102    $2.40     1,948,907  
                      

 

(1)

Represents shares of common stock remaining available for future issuance under our 2004 Equity Incentive Plan as of December 31, 2009.2010.

(2)

The 2004 Equity Incentive Plan contains an “evergreen” provision that allows for increases on the first business day of each fiscal year beginning January 1, the lesser of an additional (i) 4,000,000 shares of our common stock, (ii) 4% of the outstanding shares of common stock on the immediately preceding December 31 or (iii) an amount determined by the Board. None of our other plans has an “evergreen” provision. On December 3, 2009,November 19, 2010, the Board authorized an “evergreen” increase in the shares available for grant under the 2004 Plan in the amount of 2,498,987 shares. This increase, which was effective on January 1, 2010, representedto be equivalent to 4% of the shares of our common stock outstanding on December 31, 2009.2010, which represented an increase of 2,896,155 shares to the plan on January 1, 2011.

27


DIRECTOR COMPENSATION

The following table provides compensation information for the one year period ended December 31, 2009,2010, for each member of our Board of Directors.Board.

 

Name

  Fees Earned
or Paid in
Cash

($)
  Option
Awards
($)(1)
  All Other
Compensation
($)
  Total
($)

James N. Wilson(2)

     $716,000(2)  $132,081(2)  $848,081

Joseph K. Belanoff, M.D.(3)

              

Allen Andersson(5)

  $6,675          $6,675

G. Leonard Baker, Jr.(4)

  $15,000  $21,738       $36,738

Joseph C. Cook, Jr.(4)

  $25,000  $21,738       $46,738

Patrick G. Enright(4)

  $25,000  $21,738    $46,738

James A. Harper(4)

  $15,000  $21,738       $36,738

David L. Mahoney(4)

  $25,000  $36,230       $61,230

Edward E. Penhoet, Ph.D.(4)(6)

  $15,000  $21,738       $36,738

Name

  Fees Earned
or Paid in
Cash

($)
   Option
Awards
($)(1)
  All Other
Compensation
($)
  Total
($)
 

James N. Wilson(2)

           $363,392(2)  $363,392  

Joseph K. Belanoff, M.D.(3)

                  

G. Leonard Baker, Jr.(6)

  $15,000    $78,900(4)      $93,900  

Joseph C. Cook, Jr.(6)

  $25,000    $78,900(4)      $103,900  

Patrick G. Enright(6)

  $25,000    $78,900(4)      $103,900  

James A. Harper(6)

  $15,000    $78,900(4)      $93,900  

David L. Mahoney(6)

  $25,000    $131,500(4)      $156,500  

Joseph L. Turner(6)

  $12,500    $204,764(5)      $217,264  

 

(1)

Amounts shown do not reflect compensation actually received by the directors or the actual value that may be recognized by the directors with respect to these awards in the future. Instead, the amounts shown represent the grant date fair value of the awards. The relevant assumptions used to calculate the value of the option awards are set forth underin Part IIIV – Item 815(1) – Financial Statements, Notes to Financial Statements, Note 9 Note 1 – Accounting Policies“Preferred Stock and EstimatesStockholders’ Equity – Stock-Based Compensation Related to Employees and Director Options” in our Annual Report on Form 10-K.10-K for the year ended December 31, 2010.

 

(2)

Mr. Wilson is an employee director. He receives compensation in his role as an employee providing advice and business insight. The entire amount shown as Other Compensation for Mr. Wilson is salary paid in regard to his services as an employee. He receives no additional compensation in his capacity as a director. During 2009,2010, Mr. Wilson received cash compensation in the amount of $181,392. In addition, on December 21, 2010, our Board approved a bonus to Mr. Wilson in his capacity as an employee in the amount of $182,000 in connection with the company’s performance in 2010 that was granted an option for 400,000 shares that vests prorata over a four-year period atpaid in January 2011. See discussion under the rate of 2.0834% on the monthly anniversary“Executive Summary” and “Executive Compensation – Performance-based Compensation” sections of the date of grant, until fully vested. Including this grant, Mr. Wilson had been granted option awards totaling 650,000 shares asCompensation Discussion and Analysis. As of December 31, 2009.2010, Mr. Wilson has an aggregate number of shares represented by option awards outstanding of 650,000 shares.

 

(3)

Dr. Belanoff is a full time employee and a named executive officer and is compensated in that capacity. He receives no additional compensation in his capacity as a director. Dr. Belanoff is a named executive officer. See “Outstanding Equity Awards At Fiscal Year-End” table above for the aggregate number of shares represented by option awards outstanding that have been granted to Dr. Belanoff.

 

(4)

During 2009,2010, Mr. Mahoney, as chairman of the Audit Committee, was granted an option for 50,000 shares.shares with a grant date fair value of $131,500 and Messrs Baker, Cook, Enright, Harper and PenhoetHarper were each granted an award for 30,000 shares.shares with a grant date fair value of $78,900. All of these awards vest prorata over a one-year period at the rate of 8.3334% on the monthly anniversary of the date of grant, until fully vested. Including these grants,

(5)

In August 2010, upon joining the company as a new director, Mr. Turner was granted an initial option award for 70,000 shares with a grant date fair value of $178,500, which vests with respect to 25% of the shares on the first anniversary of the date of the grant and, thereafter, at the rate of 2.0834% per month, until fully vested. In addition, in November 2010, Mr. Turner was granted an additional option award for 10,000 shares with a grant date fair value of $26,264, upon assuming the role of chairman of the Audit Committee. This grant vests at the rate of approximately 14.2857% on the monthly anniversary of the date of grant with full vesting on or before the date of the 2011 Annual Meeting.

(6)

As of December 31, 2010, the following are the aggregate number of shares represented by option awards outstanding that have been granted to each of our non-employee directors as of December 31, 2009, the last day of the 2009 fiscal year:directors: Mr. Baker: 90,000;120,000; Mr. Cook: 135,000;165,000; Mr. Enright: 100,000;130,000; Mr. Harper: 120,000;150,000; Mr. Mahoney: 230,000 and Mr. Mahoney: 180,000. Dr. Penhoet’s aggregate options are discussed below.

(5)

The term on the Board for Mr. Andersson was completed in June 2009 at the time of our annual meeting. As of December 31, 2009, Mr. Andersson had no option awards outstanding.

(6)

Dr. Penhoet resigned from our Board of Directors, effective January 5. 2010, due to time pressures from his appointment as a member of President Obama's Council of Advisors on Science and Technology. Mr. Penhoet had originally been granted option awards for a total of 100,000 shares, which represented his aggregate outstanding options as of December 31, 2009. As of the date of his resignation, the rights to exercise 41,250 shares had vested and the unvested portions of the option awards were cancelled. Dr. Penhoet exercised his vested options on April 5, 2010.Turner: 80,000 shares.

Non-employee directors receive a director fee from us for their services as members of the Board in the amount of $15,000 per year. Members of the Audit Committee receive an additional $10,000 per year. New directors receive an initial stock option grant of 70,000 shares of our common stock in connection with their initial election to the Board. The initial director options will vest with respect to 25% of the shares on the first anniversary of the date of the grant and, thereafter, at the rate of 2.0834% per month, until fully vested. Non-employee directors who are reelected at the Annual Shareholder Meeting each receive a stock option grant that vests over the one year term as director at the rate of 8.3334% per month from the date of the Annual Meeting until fully vested. The chairmen of the Audit Committee and the Compensation Committee may each receive an additional grant of our common stock with a similar one-year vesting provision. The amounts of the annual grants are determined each year.

28


During 2009,In June 2010, David Mahoney, the chairman of the Audit Committee received a stock option grant for 50,000 shares of our stock and all other non-employee directors that were reelected in June 20092010 received grants of 30,000 shares of our common stock. In August 2010, upon joining the company as a new director, Mr. Turner was granted an initial option grant for 70,000 shares pursuant to the director compensation policy. In November 2010, Mr. Turner was granted an additional option grant for 10,000 shares upon assuming the role of chairman of the Audit Committee. Directors are reimbursed for certain expenses in connection with attending Board and committee meetings.

We have entered into a Severance and Change in Control Agreement with James N. Wilson, Chairman of the Board of Directors.Board. The agreement with Mr. Wilson provides that if his employment or service on the Board terminates involuntarily without cause or good reason within 18 months of a change in control all of his outstanding equity awards shall become fully vested. Mr. Wilson will only receive severance under this agreement if he signs and does not revoke a separation agreement and release of claims in a form reasonably acceptable to our Company within 60 days following termination of employment. No severance will be provided to Mr. Wilson until the separation agreement and release of claims becomes effective.

29


REPORT OF THE COMPENSATION COMMITTEECOMMITTEE*

The Compensation Committee of the Board, of Directors, or Compensation Committee, has furnished this report on executive compensation. None of the members of the Compensation Committee is currently our officer or employee and all are “non-employee directors” for purposes of Rule 16b-3 under the Exchange Act and “outside directors” for purposes of Section 162(m) of the Internal Revenue Code. The Compensation Committee is responsible for designing, recommending to the Board of Directors for approval and evaluating our compensation plans, policies and programs and reviewing and approving the compensation of the Chief Executive Officer and other officers and directors.

This report, filed in accordance with Item 407(e)(5) of Regulation S-K, should be read in conjunction with the other information relating to executive compensation which is contained elsewhere in this Proxy Statement and is not repeated here.

In this context, the Compensation Committee hereby reports as follows:

1. The Compensation Committee has reviewed and discussed the Compensation Discussion and Analysis sectionrequired by Item 402(b) of Regulation S-K contained herein with management.

2. Based on the review and discussions referred to in paragraph (1) above, the Compensation Committee recommended to our Board of Directors, and our Board of Directors has approved, that the Compensation Discussion and Analysis be included in this Proxy Statement and incorporated by reference to our Annual Report on Form 10-K for filing with the SEC and in this Proxy Statement.year ended December 31, 2010.

 

COMPENSATION COMMITTEE
G. LEONARDBAKER, JR., CHAIRMAN
JOSEPH C. COOK, JR.
JAMES A. HARPER
DAVID L. MAHONEY

 

30

*The material in this report is not soliciting material, and is not deemed filed with the SEC.


REPORT OF THE AUDIT COMMITTEECOMMITTEE*

Under the guidance of a written charter adopted by the Board, of Directors, the purpose of the Audit Committee is to oversee the accounting and financial reporting processes of the Company and audits of its financial statements. The responsibilities of the Audit Committee include appointing and providing for the compensation of the Company’s independent registered public accounting firm. Each of the members of the Audit Committee meets the independence requirements of NASDAQ.

Management has primary responsibility for the system of internal controls and the financial reporting process. The independent registered public accounting firm has the responsibility to express an opinion on the financial statements and internal control over financial reporting based on an audit conducted in accordance with generally accepted auditing standards.the standards of the Public Company Accounting Oversight Board (PCAOB).

In this context and in connection with the audited financial statements contained in the Company’s Annual Report on Form 10-K, the Audit Committee:

 

 · 

reviewed and discussed the audited financial statements as of and for the fiscal year ended December 31, 20092010 with the Company’s management and Ernst & Young LLP, the Company’s independent registered public accounting firm;

 

 · 

discussed with Ernst & Young LLP the matters required to be discussed by the relevant auditing standards;Statement on Auditing Standards No. 61, as amended (Codification of Statements on Auditing Standards, AU 380) as adopted by the PCAOB in Rule 3200T;

 

 · 

received the written disclosures and the letter from Ernst & Young LLP required by applicable standardsrequirements of the PCAOB regarding Ernst and Young LLP’s communications with the Audit Committee concerning independence and discussed with Ernst & Young LLP their independence,independence;

·

considered and concluded thatdiscussed whether the non-audit services, if any, performed by Ernst & Young LLP are compatible with maintaining their independence;

 

 · 

reviewed and discussed management’s reportthe reports of management and Ernst & Young LLP on its assessmenttheir assessments of the effectiveness of the Company’s internal control over financial reporting as of the end of the most recent fiscal year;

 

 · 

reviewed the disclosures regarding the Company’s system of internal controls required to be contained in the Company’s Form 10-K;

 

 · 

based on the foregoing reviews and discussions, recommended to the Board of Directors that the audited financial statements and management’s report on the effectiveness of the Company’s internal control over financial reporting as of December 31, 20092010 be included in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 20092010 filed with the Securities and Exchange Commission; and

 

 · 

instructed Ernst & Young LLP that the Audit Committee expects to be advised if there are any subjects that require special attention.

The Audit Committee has also retainedrecommended, subject to stockholder ratification in Proposal 4 in this Proxy Statement, the appointment of Ernst & Young LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2010, subject to stockholder ratification in Proposal 2 in this Proxy Statement for the Company’s 2010 Annual Meeting.2011.

AUDIT COMMITTEE

DAVIDJOSEPH L. MAHONEY,TURNER, CHAIRMAN

JOSEPH C. COOK, JR.

PATRICK G. ENRIGHT

DAVID L. MAHONEY

31

*The material in this report is not soliciting material, and is not deemed filed with the SEC.


PRINCIPALFEES OF THE INDEPENDENT REGISTERED PUBLIC ACCOUNTING FEES AND SERVICESFIRM

Audit Fees

Fees for audit services totaled approximately $642,000 in 2010 and $417,000 in 2009, and $447,000 in 2008, including fees for professional services provided by Ernst & Young LLP, our independent registered public accounting firm, in connection with the integrated annual audit of the our financial statements and internal control over financial reporting in 2010 and the annual audit of our company’s financial statements andin 2009, review of our quarterly financial statementstatements included in Quarterly Reports on Forms 10-Q, comfort letters to underwriters in connection with public financing transactions, consultations on matters addressed during the audit, quarterly reviews, or reviews of financing transactions under consideration and audit services provided in connection with other statutory or regulatory filings.filings, including consents.

Audit-Related Fees, Tax Fees, and All Other Fees

During 2010, we incurred fees for tax advisory services from our independent registered public accounting firm in the amount of approximately $19,000, in connection with our applications for grants under the United States Treasury’s Therapeutic Discovery Project Grant program. There were no fees paid to our principalindependent registered public accounting firm during 2009 or 2008 for any of these services.services in this category.

Pre-approval of audit-related and non-audit services

Our Audit Committee has adopted a policy and procedures for the pre-approval of audit and permissible non-audit services rendered by our independent registered public accounting firm, Ernst & Young LLP. Under this policy, our Audit Committee must pre-approve all audit and non-audit services performed by the Company’s independent auditor in order to ensure that the provision of such services does not impair the auditor’s independence. The policy permits the engagement of the independent registered public accounting firm for services that are approved by our Audit Committee in defined categories such as audit services, audit-related services and tax services. Pre-approval may be given as part of our Audit Committee’s annual review and approval of the scope and estimated cost of non-audit services that may be provided by the independent registered public accounting firm or on an individual explicit case-by-case basis before the independent registered public accounting firm is engaged to provide each service. The Audit Committee has also delegated to the ChairmanChair of the Audit Committee the authority to pre-approve audit-relatedaudit and non-audit services not prohibited by law to be performed by our independent registered public accounting firm and associated fees, provided that the ChairmanChair shall report any decision to pre-approve such audit-relatedaudit or non-audit services and fees to the full Audit Committee at its next regular meeting. Our Audit Committee receives periodic reports on the scope of services provided and expected to be provided by the independent registered public accounting firm in the future.

Consistent with this policy, in 2010 and 2009 all audit and non-audit services (including audit-related fees, tax fees and all other fees) performed by our independent registered public accounting firm, Ernst & Young LLP, were pre-approved by the Audit Committee.

PROPOSALS TO BE ACTED UPON AT THE ANNUAL MEETING

PROPOSAL 1

ELECTION OF DIRECTORS

At the Annual Meeting, the stockholders will vote on the election of seven directors, each to serve for a one-year term until the annual meeting of stockholders in 20112012 and until their successors are qualified and elected. The independent members of the Board have selected, and the Board has unanimously nominated, G. Leonard Baker, Jr., Joseph K. Belanoff, M.D., Joseph C. Cook, Jr., Patrick G. Enright, James A. Harper, David L. Mahoney, Joseph L. Turner and James N. Wilson for election to the Board. The nominees have indicated that they are

willing and able to serve as directors. If any of the nominees becomes unable or unwilling to serve, the accompanying proxy may be voted for the election of such other person as shall be designated by the Board. The proxies being solicited will be voted for the nominees at the Annual Meeting. Directors will be elected by a plurality of the votes cast, in person or by proxy, at the Annual Meeting, assuming a quorum is present. Stockholders do not have cumulative voting rights in the election of directors.

The Board of Directors unanimously recommends a vote “for” the election of the nominees as listed above.

Unless otherwise instructed, it is the intention of the persons named in the accompanying proxy card to vote shares represented by properly executed proxy cards for the election of the nominees as listed above.

PROPOSAL 2

ADVISORY VOTE ON

COMPENSATION OF NAMED EXECUTIVE OFFICERS

The Company’s goal for its executive compensation program is to attract and retain a talented, entrepreneurial and creative team of executives who will provide leadership for the Company’s success in managing the marketing approval by the U.S Food and Drug Administration and commercialization of CORLUX, our lead product candidate, and organizing and implementing the strategy for development of our second generation proprietary, selective GR-II compounds. The Company accomplishes this goal in a manner consistent with its strategy, competitive practice, sound corporate governance principles, and stockholder interests and concerns. The Company believes the compensation program for the named executive officers is strongly aligned with the long-term interests of its stockholders and was instrumental in helping the Company achieve strong financial performance in 2010.

Stockholders are urged to read the Executive Compensation section of this Proxy Statement, including the Compensation Discussion and Analysis, or CD&A, section which discusses the Company’s compensation policies and procedures, and the 2010 compensation for the Company’s named executive officers. The Compensation Committee and the Board believe that the Company’s compensation policies and procedures are effective in achieving the Company’s goals and are consistent with stockholder interests.

In accordance with Section 14A of the Securities Exchange Act, we are including in this Proxy Statement a separate stockholder vote on executive compensation, which vote is non-binding. Accordingly, we are asking you to approve, on an advisory basis, the compensation of the Company’s named executive officers listed in the 2010 Summary Compensation Table included in this Proxy Statement, as described in the Executive Compensation section of this Proxy Statement, including the CD&A and the related compensation tables and other narrative executive compensation disclosure contained therein.

Stockholders have the opportunity to vote “for” or “against” or to “abstain” from voting on the following non-binding resolution relating to executive compensation:

“RESOLVED, that the stockholders of the Company approve, on an advisory basis, the compensation of the Company’s named executive officers, as disclosed in the Compensation Discussion and Analysis, compensation tables and narrative discussion of this Proxy Statement.”

Although the advisory vote is non-binding, the Compensation Committee and the Board will review the results of the vote. The Compensation Committee will consider our stockholders’ concerns to the extent there is any significant vote against the named executive officer compensation as disclosed in this Proxy Statement and take them into account in future determinations concerning our executive compensation program. The Board therefore recommends that you indicate your support for the Company’s compensation policies and procedures for its named executive officers, as outlined above.

Recommendation of the Board

The Board unanimously recommends that stockholders vote, on an advisory basis, FOR the approval of the compensation of the named executive officers as described in the CD&A, the compensation tables and the narrative discussion of this Proxy Statement.

PROPOSAL 3

ADVISORY VOTE ON FREQUENCY OF VOTE

ON COMPENSATION OF NAMED EXECUTIVE OFFICERS

In accordance with Section 14A of the Securities Exchange Act, we are including in this Proxy Statement a separate stockholder vote on how frequently the advisory vote described under Proposal No. 2the “Advisory Vote on Compensation of Named Executive Officers”, or the “say on pay” advisory vote, should occur, which is referred to herein as the “frequency advisory vote”. We are providing stockholders the option of selecting a frequency of one, two or three years, or abstaining. As with the say on pay advisory vote, the vote described in this Proposal No. 3 is non-binding.

The Board has determined that providing stockholders with the say on pay advisory vote once every three years will be the most effective means for conducting and responding to the say on pay advisory vote based on a number of considerations, including the following:

·

Our compensation program is designed to induce and reward performance over a multi-year period;

·

A three-year cycle will provide investors sufficient time to evaluate the effectiveness of our short- and long-term compensation strategies and the related business outcome of the Company;

·

A three-year vote cycle gives the Board and the Compensation Committee sufficient time to thoughtfully respond to stockholders’ sentiments and to implement any necessary changes to our executive compensation policies and procedures; and

·

The Board will continue to engage with our stockholders on executive compensation during the period between stockholder votes. As discussed under “Communications with Directors,” the Company provides stockholders an opportunity to communicate with the Board, including on issues of executive compensation.

Based on the factors discussed, the Board determined to recommend that future say on pay advisory votes occur every three years until the next frequency advisory vote. Stockholders are not being asked to approve or disapprove the Board’s recommendation, but rather to indicate their choice among the following frequency options: one year, two years or three years, or to abstain from voting.

While the Board has determined that providing stockholders with the say on pay advisory vote once every three years is advisable, and therefore recommends that you approve a triennial vote, the Compensation Committee and the Board will consider our stockholders’ concerns and take them into account in determining how frequently the say on pay advisory vote occurs.

Recommendation of the Board

The Board unanimously recommends that stockholders select every “three years” on the proposal recommending the frequency of the say on pay advisory vote.

PROPOSAL 4

RATIFICATION OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

At the Annual Meeting, the stockholders will be asked to ratify the appointment of Ernst & Young LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2010.2011. Representatives of Ernst & Young LLP are expected to be present at the Annual Meeting and will have the opportunity to make statements if they desire to do so. Such representatives are also expected to be available to respond to appropriate questions.

Recommendation of the Board

The Board of Directors unanimously recommends a vote “for” the ratification of the appointment of Ernst & Young LLP as our Company’s independent registered public accounting firm for the fiscal year ending December 31, 2010.2011.

OTHER MATTERS

As of the time of preparation of this Proxy Statement, neither the Board nor management intends to bring before the meeting any business other than the matters referred to in the Notice of Annual Meeting and this Proxy Statement. If any other business should properly come before the meeting, or any adjournment or postponement thereof, the persons named in the proxy will vote on such matters according to their discretion.

32


STOCKHOLDER PROPOSALS FOR THE 20112012 ANNUAL MEETING

Our Amended and Restated Bylaws provide that advance notice of a stockholder’s proposal to be brought before the 20112012 Annual Meeting of Stockholders must be delivered to the Secretary of our Companycompany at our principal executive offices not earlier than December 22, 2010November 20, 2011 (one hundred fifty (150) days), and not later than January 21,December 20, 2011 (one hundred twenty (120) days), prior to the anniversary of the mailing date of the proxy materials for the previous year’s annual meeting. Our Amended and Restated Bylaws also provide that in the event that the annual meeting is advanced by more than 30 days prior to or delayed by more than 60 days after the anniversary date of the preceding year’s annual meeting, this advance notice must be received not later than the close of business on the later of (i) the 150th day prior to such annual meeting or (ii) the 10th day following the day on which public announcement of the date of such meeting is first made. In the event that the number of directors to be elected to the Board is increased and we do not make a public announcement naming all of the nominees for director or specifying the size of the increased Board by March 25, 2012, a stockholder’s notice required by our Amended and Restated Bylaws shall also be considered timely, but only with respect to nominees for any new positions created by such increase, if it shall be delivered to the Secretary of our company at our principal executive offices not later than the close of business on the 10th day following the day on which such public announcement is first made by us.

Each stockholder’s notice must contain the following information as to each matter the stockholder proposes to bring before the annual meeting: (a) as to each person whom the stockholder proposes to nominate for election or reelection as a director, all information relating to such person that is required to be disclosed pursuant to Regulation 14A under the Exchange Act (including such person’s written consent to being named in the proxy statement as a nominee and to serving as a director if elected) and appropriate biographical information and a statement as to the qualification of the nominee; (b) as to any other business that the stockholder proposes to bring before the meeting, a brief description of the business, the reasons for conducting such business at the meeting and any material interest in such business of such stockholder and the beneficial owner, if any, on whose behalf the proposal is made; and (c) as to the stockholder giving the notice and the beneficial owner, if any, on whose behalf the nomination or proposal is made (i) the name and address of such stockholder, as they appear on our books, and of such beneficial owner, (ii) the number of shares of our common stock which are owned

beneficially and of record by such stockholder and such beneficial owner, and (iii) whether either such stockholder or beneficial owner intends to deliver a proxy statement and form of proxy to holders of, in the case of a proposal, at least the percentage of our voting shares required under applicable law to carry the proposal or, in the case of a nomination or nominations, a sufficient number of holders of our voting shares to elect such nominee or nominees. A copy of the full text of the provisions of our Amended and Restated Bylaws dealing with stockholder nominations and proposals is available to stockholders from our Secretary upon written request.

In addition, pursuant to Rule 14a-8 under the Exchange Act, stockholder proposals for inclusion in the proxy statement of the Board of Directors for the 20112012 Annual Meeting of Stockholders must be received by us at 149 Commonwealth Drive, Menlo Park, California 94025, on or before January 21,December 20, 2011.If we are not notified by January 21,December 20, 2011 of a proposal to be brought before the 20112012 Annual Meeting by a stockholder, then proxies held by management provide the discretion to vote against such proposal even though it is not discussed in the proxy statement for such meeting.

AVAILABLE INFORMATION

We are subject to the informational requirements of the Securities Exchange Act of 1934, as amended, and, in accordance therewith, file reports, proxy statements and other information with the U.S. Securities and Exchange Commission. Reports, proxy statements and other information filed by us may be inspected without charge and copies obtained upon payment of prescribed fees from the Public Reference Section of the U.S. Securities and Exchange Commission at 100 F Street, NE, Washington, D.C. 20549, or by way of the U.S. Securities and Exchange Commission’s website at http://www.sec.gov.

We will provide without charge to each person to whom a copy of the proxy statement is delivered, upon the written or oral request of any such persons, additional copies of our Annual Report on Form 10-K for the year ended December 31, 2010 or the 2011 proxy materials. Requests for such copies should made by written request to Corcept Therapeutics Incorporated, 149 Commonwealth Drive, Menlo Park, California 94025, Attention: Secretary, or by oral request by calling (650) 327-3270.

 

By Order of the Board of Directors,

/s/ Robert L. Roe, M.D.

Robert L. Roe, M.D.
President and Secretary

Menlo Park, California

May 14, 2010April 15, 2011

33


YOUR VOTE IS IMPORTANT!

WHETHER OR NOT YOU PLAN TO ATTEND THE MEETING, PLEASE VOTE YOUR SHARES BY INTERNET, BY TELEPHONE, OR YOU CAN COMPLETE, SIGN, DATE AND MAIL PROMPTLY THE ACCOMPANYING PROXY CARD IN THE ENCLOSED RETURN ENVELOPE, WHICH REQUIRES NO POSTAGE IF MAILED IN THE UNITED STATES. THIS WILL ENSURE THE PRESENCE OF A QUORUM AT THE MEETING. IF YOU ATTEND THE MEETING, YOU MAY VOTE IN PERSON IF YOU WISH TO DO SO EVEN IF YOU HAVE PREVIOUSLY SENT IN YOUR PROXY CARD. PLEASE NOTE, HOWEVER, THAT IF YOUR SHARES ARE HELD OF RECORD BY A BROKER, BANK OR OTHER NOMINEE AND YOU WISH TO VOTE AT THE MEETING, YOU MUST OBTAIN FROM THE RECORD HOLDER A PROXY ISSUED IN YOUR NAME.

34


LOGO

CORCEPT THERAPEUTICS INCORPORATED

VOTE BY INTERNET OR TELEPHONE QUICK EASY IMMEDIATELOGO

As a stockholder of Corcept Therapeutics Incorporated, you have the option of voting your shares electronically through the Internet or on the telephone, eliminating the need to return the proxy card. Your electronic vote authorizes the named proxies to vote your shares in the same manner as if you marked, signed, dated and returned the proxy card. Votes submitted electronically over the Internet or by telephone must be received by 7:00 p.m., Eastern Time, on June 22, 2010.May 18, 2011.

LOGOLOGOLOGO

Vote Your Proxy on the Internet:

Go to www.cstproxyvote.com

Have your proxy card available when you access the above website. Follow the prompts to vote your shares.

OR  

Vote Your Proxy by Phone:

Call 1 (866) 894-0537

Use any touch-tone telephone to vote your proxy. Have your proxy card available when you call. Follow the voting instructions to vote your shares.

OR  

Vote Your Proxy by mail:

Mark, sign, and date your proxy card, then detach it, and return it in the postage-paid envelope provided.

Go to www.continentalstock.com

Have your proxy card available when

you access the above website. Follow

the prompts to vote your shares.

OR

Vote Your proxy by Phone:

Call 1 (866) 894-0537

Use any touch-tone telephone to vote

your proxy. Have your proxy card

available when you call. Follow the

voting instructions to vote your shares.

OR

Vote Your Proxy by mail:

Mark, sign, and date your proxy card,

then detach it, and return it in the

postage-paid envelope provided.

PLEASE DO NOT RETURN THE PROXY CARD IF YOU ARE VOTING ELECTRONICALLY OR BY PHONE

PLEASE DO NOT RETURN THE PROXY CARD IF YOU ARE

VOTING ELECTRONICALLY OR BY PHONE

qFOLD AND DETACH HERE AND READ THE REVERSE SIDEq

PROXY

PROXY

The Board of Directors recommends you vote FOR the election of the following nominees:

Please mark

 your votes

 like this

X

1. 

To elect seven directors, to hold office until the 2012 Annual Meeting of Stockholders and until their successors are elected and qualified, the nominees listed below:

FOR

All nominees

listed (except

as indicated

below)

WITHHOLD

AUTHORITY

to vote (as to

all nominees)

01 G. Leonard Baker, Jr.

02 Joseph K. Belanoff, M.D.

03 Joseph C. Cook, Jr.

04 Patrick G. Enright

05 David L. Mahoney

06 Joseph L. Turner

07 James N. Wilson

¨¨

To withhold authority to vote for any individual nominee, write the nominee’s name on the line provided below.

The Board of Directors recommends you vote FOR the following proposal:

2.   To approve, by non-binding vote, the compensation of our named executive officers.

¨  FOR  ¨   AGAINST  ¨   ABSTAIN

The Board of Directors recommends you vote 3 YEARS on the following proposal:

3.   To recommend, by non-binding vote, the frequency of the advisory vote on the compensation of our named executive officers.

¨   3 YEARS    ¨  2 YEARS    ¨  1 YEAR    ¨   ABSTAIN

The Board of Directors recommends you vote FOR the following proposal:

4.   To ratify the appointment of Ernst & Young LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2011.

¨  FOR  ¨   AGAINST  ¨   ABSTAIN

PROPOSALS. This proxy may be revoked by the undersigned at any time, prior to the time it is voted by any of the means described in the accompanying proxy statement.

COMPANY ID:

PROXY NUMBER:

ACCOUNT NUMBER:

1. To elect seven directors, to hold office until the 2011 Annual Meeting of Stockholders and until their successors are elected and qualified, the nominees listed below:

01 G. Leonard Baker, Jr. 05 James A. Harper

02 Joseph K. Belanoff, M.D. 06 David L. Mahoney

03 Joseph C. Cook, Jr. 07 James N. Wilson

04 Patrick G. Enright

FOR All nominees listed (except as indicated below)

WITHHOLD AUTHORITY to vote (as to all nominees)

To withhold authority to vote for any individual nominee, write the nominee’s name on the line provided below.

2. To ratify the appointment of Ernst & Young LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2010.

Please mark your votes like this X

FOR AGAINST ABSTAIN

PROPOSALS. This proxy may be revoked by the undersigned at any time, prior to the time it is voted by any of the means described in the accompanying proxy statement.

COMPANY ID:

PROXY NUMBER:

ACCOUNT NUMBER:

Signature Signature Date: , 2010.

Signature

Signature

Date:

, 2011.

Date and sign exactly as name(s) appear(s) on this proxy. If signing for estates, trusts, corporations or other entities, title or capacity should be stated. If shares are held jointly, each holder should sign.


LOGO

Important Notice Regarding the Availability of Proxy Materials for

the Annual Meeting of Stockholders to be held June 23, 2010 May 19, 2011

The 20102011 Proxy Statement and our 20092010 Annual Report are available

athttp://www.corcept.com/proxymaterials/20102011

qFOLD AND DETACH HERE AND READ THE REVERSE SIDEq

PROXY

CORCEPT THERAPEUTICS INCORPORATED

PROXY SOLICITED BY THE BOARD OF DIRECTORS

FOR THE ANNUAL MEETING OF STOCKHOLDERS

TO BE HELD JUNE 23, 2010MAY 19, 2011

The undersigned hereby appoints Joseph K. Belanoff, M.D., Caroline Loewy and James N. Wilson or any one of them with full power of substitution, proxies to vote at the Annual Meeting of Stockholders of Corcept Therapeutics (the “Company”) to be held on June 23, 2010May 19, 2011 at 10:8:00 a.m., local time, and at any adjournment or postponement thereof, hereby revoking any proxies heretofore given, to vote all shares of common stock of the Company held or owned by the undersigned as directed on the reverse side of this proxy card, and in their discretion upon such other matters as may come before the meeting.

The Board recommends that you vote FOR the proposals on the reverse side. This proxy, when properly executed, will be voted in the manner directed. WHEN NO CHOICE IS INDICATED, THIS PROXY WILL BE VOTED FOR THE PROPOSALS. Thisdirected herein. If no such direction is made, this proxy maywill be revoked byvoted in accordance with the undersigned at any time, prior to the time it is voted by anyBoard of the means described in the accompanying proxy statement.Directors’ recommendations.

(Continued, and to be marked, dated and signed, on the other side)